Probert C S, Jayanthi V, Wicks A C, Mayberry J F
Gastrointestinal Research Unit, Leicester General Hospital, UK.
Dig Dis Sci. 1993 Mar;38(3):538-41. doi: 10.1007/BF01316511.
The mortality in 1014 patients with ulcerative proctocolitis diagnosed while resident in Leicestershire identified in a population-based study from 1972 to 1989 was assessed. Ninety-two Europeans and one South Asian died. The standardized mortality ratio (SMR) in South Asians was 26 (95% confidence interval 0-147). In Europeans the overall mortality was not increased, the SMR was 93 (95% confidence interval 75-114). The SMR did not differ between established disease extents, but was highest in those patients in whom the extent was undefined (SMR = 237, 95% confidence interval 130-397). Comparison of SMRs and survival curves showed no difference in mortality in patients diagnosed from 1972 to 1980 and from 1981 to 1989. Mortality was similar in patients who had colectomy and those who had not (SMR = 130, 95% confidence interval 71-219, chi 2(1) = 1.2, NS). Mortality did not change during the study. These findings should be made available to patients and their families.
对1972年至1989年在莱斯特郡进行的一项基于人群的研究中确诊的1014例溃疡性全结肠炎患者的死亡率进行了评估。92名欧洲人和1名南亚人死亡。南亚人的标准化死亡率（SMR）为26（95%置信区间0 - 147）。在欧洲人中，总体死亡率没有增加，SMR为93（95%置信区间75 - 114）。已确定的疾病范围之间的SMR没有差异，但在疾病范围不明确的患者中最高（SMR = 237，95%置信区间130 - 397）。SMR和生存曲线的比较显示，1972年至1980年以及1981年至1989年确诊的患者在死亡率上没有差异。接受结肠切除术和未接受结肠切除术的患者死亡率相似（SMR = 130，95%置信区间71 - 219，χ2(1)=1.2，无显著性差异）。在研究期间死亡率没有变化。这些研究结果应提供给患者及其家属。
