Fernández-Fernández Leandro, Goujat-Salas Javier, Ceballos-Malagón Carmen, Tejero-Mas Manuel, Pérez-Caballero Francisco Luis, Buitrago-Ramírez Francisco
Centro de Salud de Zafra, Servicio Extremeño de Salud, Zafra, Badajoz, Spain.
Centro de Salud Obispo Paulo (Urbano 3), Servicio Extremeño de Salud, Mérida, Badajoz, Spain.
Nefrologia (Engl Ed). 2022 Nov-Dec;42(6):704-713. doi: 10.1016/j.nefroe.2023.02.005. Epub 2023 Feb 27.
Diabetes mellitus is the leading cause of chronic kidney disease (CKD) in our country. The objective was to estimate the global prevalence and by health areas of CKD in the diabetic population of Extremadura.
Observational, longitudinal retrospective study in the diabetic population attended in the Extremadura Health System in 2012-2014. A total of 90,709 patients ≥18 years old were studied. The estimated glomerular filtration rate (eGFR) was calculated using the Chronic Kidney Disease Epidemiology Collaboration equation (CKD-EPI). The presence of CKD was was defined as follows: an eGFR <60ml/min/1.73m in a time period≥of three months or the presence of renal damage, as evaluated by an urine albumin-creatinine ratio (UACR) ≥30mg/g, with or without reduced eGFR, also in a time period ≥ of three months.
The overall prevalence of CKD was 15.6% (17.5% in women and 13.7% in men) and it was higher in the province of Cáceres (17.0%) than in Badajoz (14.8%, p<0.001), with the lowest prevalence in the Navalmoral de la Mata health area (13.0%) and the highest in Plasencia (17.8%, p<0.001). The prevalence of CKD defined without the need for confirmation of the sustainability of kidney damage or decreased eGFR was 26.1% (29.3% in women and 22.9% in men), which represents an overestimation of the prevalence of 67%.
The prevalence of CKD in Extremadura's diabetic population is lower than usually referred to and differs significantly between its health areas.
糖尿病是我国慢性肾脏病（CKD）的主要病因。目的是评估埃斯特雷马杜拉糖尿病患者中CKD的全球患病率及按健康区域划分的患病率。
对2012 - 2014年在埃斯特雷马杜拉卫生系统就诊的糖尿病患者进行观察性纵向回顾性研究。共研究了90709名≥18岁的患者。使用慢性肾脏病流行病学协作组方程（CKD - EPI）计算估算肾小球滤过率（eGFR）。CKD的定义如下：在≥3个月的时间段内eGFR<60ml/min/1.73m²，或存在肾脏损害，通过尿白蛋白 - 肌酐比值（UACR）≥30mg/g评估，无论eGFR是否降低，同样在≥3个月的时间段内。
CKD的总体患病率为15.6%（女性为17.5%，男性为13.7%），卡塞雷斯省（17.0%）高于巴达霍斯省（14.8%，p<0.001），纳瓦尔莫拉尔德拉马塔健康区域患病率最低（13.0%），普拉森西亚最高（17.8%，p<0.001）。无需确认肾脏损害持续性或eGFR降低所定义的CKD患病率为26.1%（女性为29.
