职业性铅暴露对血浆硒水平影响较小。

Small effect on plasma selenium level by occupational lead exposure.

作者信息

Gustafson A, Schütz A, Andersson P, Skerfving S

机构信息

Department of Occupational Medicine, University Hospital, Lund, Sweden.

出版信息

Sci Total Environ. 1987 Oct;66:39-43. doi: 10.1016/0048-9697(87)90075-1.

DOI:10.1016/0048-9697(87)90075-1

PMID:3685956

Abstract

Selenium level in plasma (P-Se) was slightly, but statistically significantly (2p = 0.02) lower in 25 lead-exposed secondary smelter workers (P-Se 1.09 +/- 0.02 mumol l-1, mean +/- SEM; blood lead level, B-Pb, 1.9 +/- 0.1 mumol l-1) than in 25 matched controls (P-Se 1.16 +/- 0.03 mumol l-1; B-Pb 0.2 +/- 0.01 mumol l-1). Further, there was a significant negative (2p = 0.02) correlation (r = -0.33) between B-Pb and P-Se. The data indicate a minor interaction, in humans, between occupational lead exposure and selenium status.

摘要

25名铅暴露的二次冶炼厂工人血浆中的硒水平（P-Se）略低，但具有统计学意义（P = 0.02），其血浆硒水平为1.09±0.02μmol l-1（平均值±标准误；血铅水平，B-Pb，1.9±0.1μmol l-1），低于25名匹配对照组（P-Se 1.16±0.03μmol l-1；B-Pb 0.2±0.01μmol l-1）。此外，B-Pb与P-Se之间存在显著的负相关（P = 0.02）（r = -0.33）。数据表明，在人类中，职业性铅暴露与硒状态之间存在轻微相互作用。