The University of Kansas School of Medicine, Wichita, KS, USA.
Orange Park Hospital, Jacksonville, FL, USA.
Hand (N Y). 2024 Sep;19(6):904-911. doi: 10.1177/15589447231153233. Epub 2023 Mar 1.
Unconscious bias of the clinician favors the diagnosis of carpal tunnel syndrome (CTS) in patients with median paresthesia. We hypothesized that more patients in this cohort would be diagnosed with proximal median nerve entrapment (PMNE) by strengthening our cognitive awareness of this alternative diagnosis. We also hypothesized that patients with PMNE may be successfully treated with surgical release of the lacertus fibrosus (LF).
In this retrospective study, cases of median nerve decompression at the carpal tunnel and in the proximal forearm for the 2-year periods before and after adopting strategies to mitigate cognitive bias for CTS were enumerated. Patients diagnosed with PMNE and treated by LF release under local anesthesia were evaluated to determine surgical outcome at minimum 2-year follow-up. Primary outcome measures were changes in preoperative median paresthesia and proximal median-innervated muscle strength.
There was a statistically significant increase in PMNE cases identified after our heightened surveillance was initiated ( = 3.433, < .001). In 10 of 12 cases, the patient had previous ipsilateral open carpal tunnel release (CTR) but experienced recurrent median paresthesia. In 8 cases evaluated an average of 5 years after LF release, there was improvement in median paresthesia and resolution of median-innervated muscle weakness.
Owing to cognitive bias, some patients with PMNE may be misdiagnosed with CTS. All patients with median paresthesia, particularly those with persistent or recurrent symptoms after CTR, should be assessed for PMNE. Surgical release limited to the LF may be an effective treatment for PMNE.
临床医生的无意识偏见有利于诊断有正中神经感觉异常的腕管综合征(CTS)患者。我们假设通过加强对这一替代诊断的认知意识,这一队列中的更多患者将被诊断为近端正中神经受压(PMNE)。我们还假设,通过释放纤维鞘管(LF),PMNE 患者可能会得到成功治疗。
在这项回顾性研究中,对在采用减轻 CTS 认知偏见的策略前后 2 年期间接受腕管和前臂近端正中神经减压的病例进行了计数。评估在局部麻醉下通过 LF 释放治疗 PMNE 的患者,以确定至少 2 年随访时的手术结果。主要观察指标是术前正中神经感觉异常和近端正中神经支配肌肉力量的变化。
在我们开始加强监测后,PMNE 的病例数量显著增加( = 3.433, <.001)。在 12 例中,有 10 例患者之前接受过同侧开放性腕管松解术(CTR),但出现复发性正中神经感觉异常。在 8 例接受 LF 释放治疗的患者中,平均随访 5 年后,正中神经感觉异常得到改善,正中神经支配肌肉无力得到缓解。
由于认知偏见,一些 PMNE 患者可能被误诊为 CTS。所有有正中神经感觉异常的患者,尤其是那些在 CTR 后仍有持续性或复发性症状的患者,都应评估是否患有 PMNE。仅局限于 LF 的手术松解可能是 PMNE 的有效治疗方法。