Chen Shanwen, Du Maoshan, Wang Yang, Li Yifan, Tong Busheng, Qiu Jianxin, Wu Feihu, Liu Yehai
Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, P.R. China.
Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Anhui University of Chinese Medicine, 117 Meishan Road, Hefei 230031, Anhui, P.R. China.
Ther Adv Chronic Dis. 2023 Jan 18;14:20406223221148061. doi: 10.1177/20406223221148061. eCollection 2023.
Subjective tinnitus is the perception of sound in the absence of external stimulation. Neuromodulation is a novel method with promising properties for application in tinnitus management. This study sought to review the types of non-invasive electrical stimulation in tinnitus to provide the foothold for further research. PubMed, EMBASE, and Cochrane databases were searched for studies on the modulation of tinnitus by non-invasive electrical stimulation. Among the four forms of non-invasive electrical modulation, transcranial direct current stimulation, transcranial random noise stimulation, and transauricular vagus nerve stimulation yielded promising results, whereas the effect of transcranial alternating current stimulation in the treatment of tinnitus has not been confirmed. Non-invasive electrical stimulation can effectively suppress tinnitus perception in some patients. However, the heterogeneity in parameter settings leads to scattered and poorly replicated findings. Further high-quality studies are needed to identify optimal parameters to develop more acceptable protocols for tinnitus modulation.
主观性耳鸣是指在没有外部刺激的情况下对声音的感知。神经调节是一种具有应用于耳鸣治疗的前景良好特性的新方法。本研究旨在回顾耳鸣的非侵入性电刺激类型，为进一步研究提供立足点。在PubMed、EMBASE和Cochrane数据库中检索关于非侵入性电刺激对耳鸣调节作用的研究。在四种非侵入性电调制形式中，经颅直流电刺激、经颅随机噪声刺激和经耳迷走神经刺激取得了有前景的结果，而经颅交流电刺激治疗耳鸣的效果尚未得到证实。非侵入性电刺激可有效抑制部分患者的耳鸣感知。然而，参数设置的异质性导致研究结果分散且难以重复。需要进一步的高质量研究来确定最佳参数，以制定更可接受的耳鸣调制方案。
