Narita Masahiko, Tsutsui Masahiro, Ushioda Ryouhei, Kikuchi Yuta, Shirasaka Tomonori, Ishikawa Natsuya, Kamiya Hiroyuki
Department of Cardiac Surgery, Asahikawa Medical University, Asahikawa, Japan.
Front Surg. 2023 Feb 13;10:1081167. doi: 10.3389/fsurg.2023.1081167. eCollection 2023.
This study aimed to compare the short- and long-term outcomes of proximal repair vs. extensive arch surgery for acute DeBakey type I aortic dissection.
From April 2014 to September 2020, 121 consecutive patients with acute type A dissection were surgically treated at our institute. Of these patients, 92 had dissections extending beyond the ascending aorta.
Of the 92 patients, 58 underwent proximal repair, including aortic root and/or hemiarch replacement, and 34 underwent extended repair, including partial and total arch replacement. Perioperative variables and early and late postoperative results were statistically analyzed.
The duration of surgery, cardiopulmonary bypass, and circulatory arrest was significantly shorter in the proximal repair group (< 0.01). The overall operative mortality rate was 10.3% in the proximal repair group and 14.7% in the extended repair group (= 0.379). The mean follow-up period was 31.1 ± 26.7 months in the proximal repair group and 35.3 ± 26.8 months in the extended repair group. During follow-up, the cumulative survival and freedom from reintervention rates at 5 years were 66.4% and 92.9% in the proximal repair group, and 76.1% and 72.6% in the extended repair group, respectively (= 0.515 and = 0.134).
No significant differences were found in the rates of long-term cumulative survival and freedom from aortic reintervention between the two surgical strategies. These findings suggest limited aortic resection achieves acceptable patient outcomes.
本研究旨在比较急性DeBakey I型主动脉夹层近端修复术与广泛弓部手术的短期和长期结果。
2014年4月至2020年9月,我院对121例连续的急性A型夹层患者进行了手术治疗。其中,92例患者的夹层延伸至升主动脉以外。
92例患者中,58例行近端修复术,包括主动脉根部和/或半弓置换术;34例行广泛修复术,包括部分和全弓置换术。对围手术期变量以及术后早期和晚期结果进行统计学分析。
近端修复组的手术时间、体外循环时间和循环阻断时间明显更短(<0.01)。近端修复组的总体手术死亡率为10.3%,广泛修复组为14.7%(P = 0.379)。近端修复组的平均随访期为31.1±26.7个月,广泛修复组为35.3±26.8个月。随访期间,近端修复组5年的累积生存率和免于再次干预率分别为66.4%和92.9%,广泛修复组分别为76.1%和72.6%(P = 0.515和P = 0.134)。
两种手术策略在长期累积生存率和免于主动脉再次干预率方面没有显著差异。这些发现表明,有限的主动脉切除术能取得可接受的患者预后。