Graduate Programme in Health Sciences and Technologies, University of Brasilia, Brasilia, Brazil (Ms Oliveira Milani and Drs Mauricio Milani, Cipriano, and Cipriano Junior); Fitcordis Exercise Medicine Clinic, Brasilia, Brazil (Ms Oliveira Milani and Dr Mauricio Milani); Rehabilitation Sciences Programme, University of Brasilia, Brasilia, Brazil (Drs Cipriano and Cipriano Junior); Rheumatology Division, School of Medicine, University of São Paulo, São Paulo, Brazil (Dr de Castro); Hasselt University, REVAL/BIOMED, Hasselt, Belgium (Ms Oliveira Milani and Dr Hansen); and Heart Centre Hasselt, Jessa Hospital, Hasselt, Belgium (Dr Hansen).
J Cardiopulm Rehabil Prev. 2023 Jul 1;43(4):290-300. doi: 10.1097/HCR.0000000000000778. Epub 2023 Mar 3.
The purpose of this study is to provide comprehensive reference values for oxygen uptake efficiency slope (OUES) in healthy adults. International heterogeneity was also explored through published databases.
A cross-sectional study was conducted with treadmill cardiopulmonary exercise testing (CPX) from a Brazilian healthy adult sample, in which absolute OUES and values normalized by weight and body surface area (BSA) were calculated. Data were stratified by sex and age group. Prediction equations were calculated using age and anthropometric variables. International data were pooled and differences were explored using factorial analysis of variance or the t test, as appropriate. The OUES age-related patterns were calculated using regression analysis.
A total of 3544 CPX were included (1970 males and 1574 females) and the age ranged from 20-80 yr. Males had higher values than females for OUES, OUES/kg, and OUES/BSA. Lower values were found with aging and the data followed a quadratic regression curve. Reference value tables and predictive equations were provided for absolute and normalized OUES in both sexes. International comparisons of absolute OUES values among Brazilian, European, and Japanese data revealed substantial heterogeneity. The OUES/BSA measure minimized the discrepancies between Brazilian and European data.
Our study provided comprehensive OUES reference values in a large healthy adult sample from South America with a wide age range and included absolute and normalized values. Differences observed between Brazilian and European data were reduced in the BSA-normalized OUES.
本研究旨在为健康成年人的摄氧量效率斜率(OUES)提供全面的参考值。还通过已发表的数据库探索了国际异质性。
对来自巴西健康成年人样本的跑步机心肺运动测试(CPX)进行了横断面研究,其中计算了绝对 OUES 和按体重和体表面积(BSA)归一化的值。数据按性别和年龄组分层。使用年龄和人体测量学变量计算预测方程。汇总国际数据,并使用方差分析或 t 检验(视情况而定)探索差异。使用回归分析计算与年龄相关的 OUES 模式。
共纳入 3544 次 CPX(1970 名男性和 1574 名女性),年龄范围为 20-80 岁。男性的 OUES、OUES/kg 和 OUES/BSA 值高于女性。随着年龄的增长,数值降低,数据遵循二次回归曲线。提供了男女绝对和归一化 OUES 的参考值表和预测方程。对巴西、欧洲和日本数据的绝对 OUES 值进行国际比较显示出很大的异质性。BSA 归一化的 OUES 最大限度地减少了巴西和欧洲数据之间的差异。
我们的研究在南美的一个健康成年人样本中提供了全面的 OUES 参考值,该样本具有广泛的年龄范围,包括绝对和归一化值。在 BSA 归一化的 OUES 中,观察到的巴西和欧洲数据之间的差异减少了。