Department of Rehabilitation Sciences, KU Leuven, Belgium
Department of Rehabilitation Sciences, KU Leuven, Belgium.
Eur J Prev Cardiol. 2015 Mar;22(3):356-63. doi: 10.1177/2047487314547658. Epub 2014 Aug 21.
The oxygen uptake efficiency slope (OUES) has been proposed as an independent, reproducible and objective measure of cardiorespiratory function that does not require maximal exercise testing. Existing reference values have been published for healthy paediatric populations and healthy elderly. However, reference ranges and equations for healthy adults of working age are insufficiently documented. The aim of the present study was to establish prediction equations and to describe reference values for healthy men and women aged 20-60 years.
Cross-sectional study.
One thousand four hundred and eleven (877 men) healthy individuals (mean age 38.6 years; range 20-60) completed a maximal graded cycle exercise test until volitional exhaustion. Subsequently, oxygen uptake was plotted against the logarithm of total ventilation and the OUES was calculated by means of linear regression analysis.
Multivariate regression analyses revealed age, sex and body surface area as statistically significant determinants of the OUES. Following this, sex-specific prediction equations for the OUES were established and cross-validated. Finally, the distribution of the OUES with age was described and reference values were established for men and women separately.
This study established a comprehensive set of reference values and reference equations for the OUES for a healthy population of men and women aged between 20 and 60 years.
摄氧量效率斜率（OUES）已被提出作为一种独立的、可重复的和客观的心肺功能测量方法，不需要最大运动测试。现有的参考值已经发布用于健康的儿科人群和健康的老年人。然而，对于工作年龄的健康成年人的参考范围和方程记录不足。本研究的目的是建立预测方程，并描述 20-60 岁健康男性和女性的参考值。
横断面研究。
1411 名（877 名男性）健康个体（平均年龄 38.6 岁；范围 20-60）完成了最大递增循环运动测试直至自愿衰竭。随后，将摄氧量与总通气量的对数作图，并通过线性回归分析计算 OUES。
多变量回归分析显示年龄、性别和体表面积是 OUES 的统计学显著决定因素。在此基础上，建立了 OUES 的性别特异性预测方程，并进行了交叉验证。最后，描述了 OUES 随年龄的分布，并分别为男性和女性建立了参考值。
本研究为 20-60 岁健康男性和女性人群建立了一套全面的 OUES 参考值和参考方程。
