Schweigel J F, Berezowskyj J
Department of Orthopaedic Surgery, Shaughnessy Hospital/University of British Columbia, Vancouver.
Spine (Phila Pa 1976). 1987 Oct;12(8):800-2. doi: 10.1097/00007632-198710000-00017.
In this review of 35 patients who received repeat chymopapain injections, 41% had an excellent result, 37% had some improvement, and 22% showed no improvement. Of the 21 patients followed who had the same disc injected twice, 43% had an excellent result and 24% had no improvement. Of the three patients followed who had a different disc injected on the second occasion, one had an excellent result, and none showed no improvement. There was no significant difference between the two groups. Six patients (17%) had an anaphylactic reaction to the second injection. Five had a major reaction. Repeat chymopapain injection may be a valid treatment for a protruded disc but should not be performed until a definitive test for sensitivity is developed.
在这篇对35例接受重复木瓜凝乳蛋白酶注射患者的综述中，41%效果极佳，37%有一定改善，22%无改善。在接受同一椎间盘两次注射的21例随访患者中，43%效果极佳，24%无改善。在接受第二次注射时注射不同椎间盘的3例随访患者中，1例效果极佳，无人无改善。两组之间无显著差异。6例患者（17%）对第二次注射有过敏反应。5例有严重反应。重复木瓜凝乳蛋白酶注射可能是治疗椎间盘突出的有效方法，但在开发出确定的敏感性检测方法之前不应进行。
