Traditional Chinese Medicine Department of Wuhan No.1 Hospital, China.
Medicine (Baltimore). 2023 Mar 3;102(9):e33131. doi: 10.1097/MD.0000000000033131.
Metaplastic breast cancer (MBC) is a rare tumor of the breast, and skin ulceration of breast tumors is a difficult clinical problem that reduces the patient's quality of life.
There are currently no Standard Treatment Guidelines for MBC at present, and the treatment for the skin ulceration of breast tumors is limited in clinics.
Here, we report the case of a patient with a large MBC and skin ulceration, accompanied by exudation and odor.
The combined treatment of albumin paclitaxel and carrelizumab (anti-PD-1 immunotherapy) was effective in reducing the tumor, but it increased the severity of the skin ulceration. After taking traditional Chinese medicine, the skin ulceration healed completely. Then the patient underwent a mastectomy and radiotherapy.
The patient has a high quality of life and was in good condition after the comprehensive treatment.
This suggests that traditional Chinese medicine may have a good auxiliary therapeutic effect on the skin ulceration of MBC.
化生性乳腺癌（MBC）是一种罕见的乳腺肿瘤，而乳腺肿瘤的皮肤溃疡是一个临床难题，降低了患者的生活质量。
目前，MBC 没有标准的治疗指南，且临床上对乳腺肿瘤皮肤溃疡的治疗方法有限。
我们在此报告 1 例伴有渗出和异味的大型 MBC 伴皮肤溃疡患者。
白蛋白紫杉醇联合卡瑞利珠单抗（抗 PD-1 免疫治疗）的联合治疗可有效缩小肿瘤，但使皮肤溃疡的严重程度增加。经中药治疗后，皮肤溃疡完全愈合。随后患者接受了乳房切除术和放疗。
患者生活质量高，综合治疗后情况良好。
这表明，中药可能对 MBC 的皮肤溃疡有较好的辅助治疗作用。
