Departments of Psychiatry and Neurology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA; Translational Neuroscience Lab Division, Center for Biomedical Imaging and Neuromodulation, Nathan Kline Institute, Orangeburg, NY 10962, USA; Cognitive Science Department, Institute of Philosophy, Jagiellonian University, Krakow 31-007, Poland.
Translational Neuroscience Lab Division, Center for Biomedical Imaging and Neuromodulation, Nathan Kline Institute, Orangeburg, NY 10962, USA; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY 11030, USA; Departments of Neurosurgery and Neurology, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY 11549, USA.
Curr Biol. 2023 Apr 10;33(7):1185-1195.e6. doi: 10.1016/j.cub.2023.02.018. Epub 2023 Mar 1.
In natural "active" vision, humans and other primates use eye movements (saccades) to sample bits of information from visual scenes. In the visual cortex, non-retinal signals linked to saccades shift visual cortical neurons into a high excitability state as each saccade ends. The extent of this saccadic modulation outside of the visual system is unknown. Here, we show that during natural viewing, saccades modulate excitability in numerous auditory cortical areas with a temporal pattern complementary to that seen in visual areas. Control somatosensory cortical recordings indicate that the temporal pattern is unique to auditory areas. Bidirectional functional connectivity patterns suggest that these effects may arise from regions involved in saccade generation. We propose that by using saccadic signals to yoke excitability states in auditory areas to those in visual areas, the brain can improve information processing in complex natural settings.
在自然的“主动”视觉中，人类和其他灵长类动物通过眼球运动（扫视）从视觉场景中采样信息片段。在视觉皮层中，与扫视相关的非视网膜信号会在每次扫视结束时将视觉皮层神经元转移到高兴奋性状态。这种扫视调制在视觉系统之外的程度尚不清楚。在这里，我们表明在自然观察期间，扫视以与视觉区域中所见互补的时间模式调制众多听觉皮层区域的兴奋性。对照体感皮质记录表明，这种时间模式是听觉区域特有的。双向功能连接模式表明，这些影响可能来自于参与扫视生成的区域。我们提出，通过使用扫视信号将听觉区域的兴奋性状态与视觉区域的兴奋性状态联系起来，大脑可以在复杂的自然环境中改善信息处理。
