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肾移植术后血管并发症的介入治疗。

Interventional Management of Vascular Complications after Renal Transplantation.

机构信息

Department of Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Germany.

Department of Medicine IV, Medical Center-University of Freiburg, Germany.

出版信息

Rofo. 2023 Jun;195(6):495-504. doi: 10.1055/a-2007-9649. Epub 2023 Mar 2.

Abstract

BACKGROUND

Kidney transplantations are increasing due to demographic changes and are the treatment of choice for end-stage renal disease. Non-vascular and vascular complications may occur in the early phase after transplantation and at later stages. Overall postoperative complications after renal transplantations occur in approximately 12 % to 25 % of renal transplant patients. In these cases, minimally invasive therapeutic interventions are essential to ensure long-term graft function. This review article focuses on the most critical vascular complications after renal transplantation and highlights current recommendations for interventional treatment.

METHOD

A literature search was performed in PubMed using the search terms "kidney transplantation", "complications", and "interventional treatment". Furthermore, the 2022 annual report of the German Foundation for Organ Donation and the EAU guidelines for kidney transplantation (European Association of Urology) were considered.

RESULTS AND CONCLUSION

Image-guided interventional techniques are favorable compared with surgical revision and should be used primarily for the treatment of vascular complications. The most common vascular complications after renal transplantation are arterial stenoses (3 %-12.5 %), followed by arterial and venous thromboses (0.1 %-8.2 %) and dissection (0.1 %). Less frequently, arteriovenous fistulas or pseudoaneurysms occur. In these cases, minimally invasive interventions show a low complication rate and good technical and clinical results. Diagnosis, treatment, and follow-up should be performed in an interdisciplinary approach at highly specialized centers to ensure the preservation of graft function. Surgical revision should be considered only after exhausting minimally invasive therapeutic strategies.

KEY POINTS

· Vascular complications after renal transplantation occur in 3 % to 15 % of patients.. · Image-guided interventional procedures should be performed primarily to treat vascular complications of renal transplantation.. · Minimally invasive interventions have a low complication rate with good technical and clinical outcomes..

CITATION FORMAT

· Verloh N, Doppler M, Hagar MT et al. Interventional Management of Vascular Complications after Renal Transplantation. Fortschr Röntgenstr 2023; 195: 495 - 504.

摘要

背景

由于人口结构的变化,肾移植数量不断增加,并且是终末期肾病的首选治疗方法。肾移植后早期和晚期可能会出现非血管和血管并发症。肾移植后,大约有 12%至 25%的患者会出现术后总体并发症。在这些情况下,微创治疗干预对于确保长期移植物功能至关重要。本文重点介绍肾移植后最关键的血管并发症,并强调当前介入治疗的建议。

方法

使用“肾移植”、“并发症”和“介入治疗”等关键词在 PubMed 上进行文献检索。此外,还考虑了德国器官捐赠基金会 2022 年年度报告和 EAU 肾移植指南(欧洲泌尿外科学会)。

结果和结论

与手术修正相比,基于影像的介入技术更具优势,应主要用于治疗血管并发症。肾移植后最常见的血管并发症是动脉狭窄(3%至 12.5%),其次是动脉和静脉血栓形成(0.1%至 8.2%)和夹层(0.1%)。较少见的是动静脉瘘或假性动脉瘤。在这些情况下,微创介入具有较低的并发症发生率和良好的技术和临床效果。为了确保移植物功能的保留,应在高度专业化的中心以多学科方式进行诊断、治疗和随访。只有在穷尽微创治疗策略后,才应考虑手术修正。

关键点

·肾移植后血管并发症在 3%至 15%的患者中发生。·应主要通过影像引导的介入程序来治疗肾移植的血管并发症。·微创介入具有较低的并发症发生率和良好的技术及临床效果。

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