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Gene Expression Profiling Suggests that Complement Activation Is Important for Blister Formation in Bullous Pemphigoid.

作者信息

Lamberts Aniek, Kotnik Nika, Meijer Joost M, van Kempen Leon C, Diercks Gilles F H, Horváth Barbara

机构信息

Center for Blistering Diseases, Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Center for Blistering Diseases, Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Division of Experimental Allergology and Immunodermatology, Department of Medicine, University of Oldenburg, Oldenburg, Germany.

出版信息

J Invest Dermatol. 2023 Aug;143(8):1591-1594.e2. doi: 10.1016/j.jid.2023.01.029. Epub 2023 Feb 28.

DOI:10.1016/j.jid.2023.01.029
PMID:36863446
Abstract
摘要

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IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes.大疱性类天疱疮中的IgG自身抗体在角质形成细胞中诱导致病性的依赖MyD88的促炎反应。
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Exploring Pruritus in Bullous Pemphigoid: Analysis of QOL Metrics and Potential Biological Mechanisms.大疱性类天疱疮瘙痒的探索:生活质量指标及潜在生物学机制分析
JID Innov. 2024 Nov 21;5(2):100329. doi: 10.1016/j.xjidi.2024.100329. eCollection 2025 Mar.
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Associated factors related to production of autoantibodies and dermo-epidermal separation in bullous pemphigoid.
大疱性类天疱疮中与自身抗体产生及皮肤表皮分离相关的因素。
Arch Dermatol Res. 2025 Jan 24;317(1):303. doi: 10.1007/s00403-024-03760-0.