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胰腺壁内坏死的内镜治疗

Endoscopic management of pancreatic walled-off necrosis.

作者信息

Ramai Daryl, Morgan Amanda D, Gkolfakis Paraskevas, Facciorusso Antonio, Chandan Saurabh, Papaefthymiou Apostolis, Morris John, Arvanitakis Marianna, Adler Douglas G

机构信息

Gastroenterology & Hepatology, University of Utah Health, Salt Lake City, UT, USA (Daryl Ramai, John Morris).

Rocky Vista University, Ivins, UT, USA (Amanda D. Morgan).

出版信息

Ann Gastroenterol. 2023 Mar-Apr;36(2):123-131. doi: 10.20524/aog.2023.0772. Epub 2023 Jan 4.

DOI:10.20524/aog.2023.0772
PMID:36864934
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9932860/
Abstract

Pancreatic walled-off necrosis (WON) is a complication of severe pancreatitis. Endoscopic transmural drainage has been recognized as the first-line treatment for pancreatic fluid collections. Endoscopy offers a minimally invasive approach when compared to surgical drainage. Today, endoscopists may choose to use self-expanding metal stents, pigtail stents, or lumen-apposing metal stents to facilitate drainage of fluid collections. Current data suggest that all 3 approaches yield similar outcomes. It was previously thought that drainage should be performed 4 weeks from the initial event of pancreatitis, theoretically allowing the capsule to mature. However, current data show that both early (<4 weeks) and standard (≥4 weeks) endoscopic drainage are comparable. Herein, we provide an up-to-date state-of-the-art review of the indications, techniques, innovations, outcomes, and future perspectives following drainage of pancreatic WON.

摘要

胰腺包裹性坏死(WON)是重症胰腺炎的一种并发症。内镜下经壁引流已被公认为胰腺液体积聚的一线治疗方法。与手术引流相比,内镜检查提供了一种微创方法。如今,内镜医师可选择使用自膨式金属支架、猪尾支架或管腔贴附金属支架来促进液体积聚的引流。目前的数据表明,这三种方法产生的结果相似。以前认为应在胰腺炎初始事件发生4周后进行引流,理论上可使包膜成熟。然而,目前的数据显示,早期(<4周)和标准(≥4周)内镜引流效果相当。在此,我们提供了一篇关于胰腺WON引流后的适应症、技术、创新、结果及未来展望的最新技术综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/15d12ca70666/AnnGastroenterol-36-123-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/c5483daecea7/AnnGastroenterol-36-123-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/a644422fe50d/AnnGastroenterol-36-123-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/efa18337b63e/AnnGastroenterol-36-123-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/d7f320cd0b38/AnnGastroenterol-36-123-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/83119b52cf50/AnnGastroenterol-36-123-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/f4e45c38c64c/AnnGastroenterol-36-123-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/15d12ca70666/AnnGastroenterol-36-123-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/c5483daecea7/AnnGastroenterol-36-123-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/a644422fe50d/AnnGastroenterol-36-123-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/efa18337b63e/AnnGastroenterol-36-123-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/d7f320cd0b38/AnnGastroenterol-36-123-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/83119b52cf50/AnnGastroenterol-36-123-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/f4e45c38c64c/AnnGastroenterol-36-123-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00d5/9932860/15d12ca70666/AnnGastroenterol-36-123-g008.jpg

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Gastrointest Endosc. 2023 Mar;97(3):415-421.e5. doi: 10.1016/j.gie.2022.11.003. Epub 2022 Nov 15.
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Surg Endosc. 2025 Mar;39(3):1449-1461. doi: 10.1007/s00464-024-11522-2. Epub 2025 Jan 23.
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