Chen Yang, Guo Hao, Dong Peng, Li Yue, Zhang Zhongsheng, Mao Ning, Chu Tongpeng, Sun Zehua, Wang Fang, Feng Zhiqiang, Wang Huaying, Ma Heng
Department of Medical Imaging, Weifang Medical University, Weifang, China.
Department of Radiology, Qingdao University and Yantai Yuhuangding Hospital, Yantai, China.
Cardiovasc Diagn Ther. 2023 Feb 28;13(1):51-60. doi: 10.21037/cdt-22-487. Epub 2022 Dec 29.
Coronary artery disease (CAD) is one of the most common diseases seriously harmful to human health caused by atherosclerosis. Besides coronary computed tomography angiography (CCTA) and invasive coronary angiography (ICA), coronary magnetic resonance angiography (CMRA) has become an alternative examination. The purpose of this study was to prospectively evaluate the feasibility of 3.0 T free-breathing whole-heart non-contrast-enhanced coronary magnetic resonance angiography (NCE-CMRA).
After Institutional Review Board approval, the NCE-CMRA data sets of 29 patients acquired successfully at 3.0 T were evaluated independently by two blinded readers for visualization and image quality of coronary arteries using the subjective quality grade. The acquisition times were recorded in the meantime. A part of the patients had undergone CCTA, we represented stenosis by scores and used the Kappa to evaluate the consistency between CCTA and NCE-CMRA.
Six patients did not get diagnostic image quality because of severe artifacts. The image quality score assessed by both radiologists is 3.2±0.7, which means the NCE-CMRA can show the coronary arteries excellently. The main vessels of the coronary artery on NCE-CMRA images are considered reliably assessable. The acquisition time of NCE-CMRA, is 8.8±1.2 min. The Kappa of CCTA and NCE-CMRA on detecting stenosis is 0.842 (P<0.001).
The NCE-CMRA results in reliable image quality and visualization parameters of coronary arteries within a short scan time. The NCE-CMRA and CCTA have a good agreement for detecting stenosis.
冠状动脉疾病（CAD）是由动脉粥样硬化引起的最常见且严重危害人类健康的疾病之一。除了冠状动脉计算机断层扫描血管造影（CCTA）和有创冠状动脉血管造影（ICA）外，冠状动脉磁共振血管造影（CMRA）已成为一种替代检查方法。本研究的目的是前瞻性评估3.0 T自由呼吸全心非对比增强冠状动脉磁共振血管造影（NCE-CMRA）的可行性。
经机构审查委员会批准后，由两名盲法阅片者独立评估在3.0 T成功采集的29例患者的NCE-CMRA数据集，使用主观质量等级评估冠状动脉的可视化和图像质量。同时记录采集时间。部分患者已接受CCTA检查，我们用评分表示狭窄程度，并使用Kappa值评估CCTA与NCE-CMRA之间的一致性。
6例患者因严重伪影未获得诊断性图像质量。两位放射科医生评估的图像质量评分为3.2±0.7，这意味着NCE-CMRA能够很好地显示冠状动脉。NCE-CMRA图像上冠状动脉的主要血管被认为可可靠评估。NCE-CMRA的采集时间为8.8±1.2分钟。CCTA与NCE-CMRA在检测狭窄方面的Kappa值为0.842（P<0.001）。
NCE-CMRA在短扫描时间内可获得可靠的冠状动脉图像质量和可视化参数。NCE-CMRA与CCTA在检测狭窄方面具有良好的一致性。
