Hitchins Margaret R, Bouchard Jeannette L, Ingram Christopher W, Orvin Alison I
Department of Pharmacy, WakeMed Health and Hospitals, Raleigh, North Carolina.
University of North Carolina Eshelman School of Pharmacy, Chapel Hill, North Carolina.
Antimicrob Steward Healthc Epidemiol. 2023 Feb 27;3(1):e37. doi: 10.1017/ash.2023.117. eCollection 2023.
We evaluated the impact of an asymptomatic bacteriuria (ASB) assessment protocol on the number of antibiotics prescribed for ASB after discharge from the emergency department (ED).
Single-center, before-and-after, retrospective cohort study.
The study was conducted at a large community health system in North Carolina.
Eligible patients were discharged from an ED without an antibiotic prescription and had a positive urine culture result after discharge from May through July 2021 (preimplementation group) and October through December 2021 (postimplementation group).
Patient records were reviewed to determine the number of antibiotic prescriptions for ASB on follow-up call before and after implementation of an ASB assessment protocol. Secondary outcomes included 30-day admissions, 30-day ED visits, 30-day UTI-related encounters, and projected antibiotic days of therapy.
The study included 263 patients: 147 in the preimplementation group and 116 in the postimplementation group). There were significantly fewer antibiotic prescriptions for ASB in the postimplementation group (50% vs 87%; P < .0001). There were no differences in the incidence of 30-day admissions (7% vs 8%; P = .9761), 30-day ED visits (14% vs 16%; P = .7805), or 30-day UTI-related encounters (0% vs 0%, NA).
Implementation of an ASB assessment protocol for patients discharged from the ED significantly reduced the number of antibiotic prescriptions for ASB on follow-up call without an increase in 30-day admissions, ED visits, or UTI-related encounters.
我们评估了无症状菌尿(ASB)评估方案对急诊科(ED)出院后因ASB开具的抗生素数量的影响。
单中心、前后对照、回顾性队列研究。
该研究在北卡罗来纳州的一个大型社区卫生系统中进行。
符合条件的患者于2021年5月至7月(实施前组)和2021年10月至12月(实施后组)从ED出院时未开具抗生素处方,出院后尿培养结果呈阳性。
审查患者记录,以确定在实施ASB评估方案前后随访电话中因ASB开具的抗生素处方数量。次要结局包括30天内再次入院、30天内急诊就诊、30天内与UTI相关的就诊,以及预计的抗生素治疗天数。
该研究纳入了263例患者:实施前组147例,实施后组116例。实施后组因ASB开具的抗生素处方明显减少(50%对87%;P <.0001)。30天内再次入院率(7%对8%;P =.9761)、30天内急诊就诊率(14%对16%;P =.7805)或30天内与UTI相关的就诊率(0%对0%,无可用数据)没有差异。
对从ED出院的患者实施ASB评估方案可显著减少随访电话中因ASB开具的抗生素处方数量,且不会增加30天内再次入院、急诊就诊或与UTI相关的就诊次数。