Chaturvedi Saurabh, Chaturvedi Yogita, Chowdhary Seema, Kararia Nitin, Kararia Vandana, Goyal Deepak
Department of Orthodontics and Dentofacial Orthopedics, Government Dental College, Rajasthan University of Health Sciences (CDS), Jaipur, Rajasthan, India.
MDS Pedodontics, Private Practitioner, Jaipur, Rajasthan, India.
Int J Clin Pediatr Dent. 2022 Sep-Oct;15(5):520-524. doi: 10.5005/jp-journals-10005-2447.
Children with congenital or acquired craniofacial abnormalities exhibit an array of dental abnormalities like supernumerary teeth, failure of permanent teeth eruption, decreased alveolar bone height, etc. These subjects undergo complex corrective surgeries to improve esthetics and functional derangements, predisposing them to risks of obstructive sleep apnea due to airway obstruction. The various corrective or therapeutic procedures done might lead to airway complications in these children. The study designed was for retrospective evaluation and comparison of the nasopharyngeal (NP) characteristics and assessment of the airway volume three-dimensionally in normal vs cleidocranial subjects.
Cone-beam computed tomography (CBCT) scans of nine subjects with cleidocranial dysplasia (CCD) were compared with the control sample, and matched for age and sex. A 3D-DOCTOR software by Able Software Corporation was used to calculate the volumetric measurements. The correlation and differences among the values were assessed using an independent -test and Pearson analysis.
The values of lower airway width, upper adenoid width, McNamara upper pharynx, retroglossal area, and total pharyngeal area were found to be reduced in the cleidocranial subjects. The NP airway volume and total airway volume also significantly decreased.
Cleidocranial dysplasia (CCD) being a rare genetic disorder, we could find only nine established cases. Hence our study can be called a pilot study but may work to establish a database of any sort of skeletal and dental anomaly with possible specific respiratory characteristics affecting airway.
Chaturvedi S, Chaturvedi Y, Chowdhary S, et A Three-dimensional Analysis of Nasopharyngeal Airway Characteristics in Subjects with Cleidocranial Dysplasia: A CBCT Study. Int J Clin Pediatr Dent 2022;15(5):520-524.
患有先天性或后天性颅面畸形的儿童表现出一系列牙齿异常，如多生牙、恒牙萌出失败、牙槽骨高度降低等。这些患儿需要接受复杂的矫正手术以改善美观和功能紊乱，这使他们因气道阻塞而面临阻塞性睡眠呼吸暂停的风险。所进行的各种矫正或治疗程序可能会导致这些儿童出现气道并发症。本研究旨在对正常儿童与锁骨颅骨发育不全患儿的鼻咽（NP）特征进行回顾性评估和比较，并对气道容积进行三维评估。
将9例锁骨颅骨发育不全（CCD）患儿的锥形束计算机断层扫描（CBCT）图像与对照样本进行比较，并根据年龄和性别进行匹配。使用Able软件公司的3D-DOCTOR软件计算容积测量值。使用独立t检验和Pearson分析评估这些值之间的相关性和差异。
发现锁骨颅骨发育不全患儿的下气道宽度、腺样体上缘宽度、麦克纳马拉上咽部、舌后区域和总咽部面积值均降低。NP气道容积和总气道容积也显著减小。
锁骨颅骨发育不全（CCD）是一种罕见的遗传性疾病，我们仅找到9例确诊病例。因此，我们的研究可称为一项初步研究，但可能有助于建立一个包含任何可能影响气道的具有特定呼吸特征的骨骼和牙齿异常的数据库。
Chaturvedi S, Chaturvedi Y, Chowdhary S等。锁骨颅骨发育不全患儿鼻咽气道特征的三维分析：一项CBCT研究。《国际临床儿科牙科学杂志》2022；15(5):520 - 524。
