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“口罩痘”患者与脂溢性皮炎患者及健康个体的马拉色菌定植情况比较

Comparison of Malassezia Colonization of 'Maskne' Patients with Seborrheic Dermatitis Cases and Healthy Individuals.

作者信息

Atsü Ayse N, Caf Nazlı, Türkoğlu Zafer, Özkoca Defne, Yıldırım Ozan, Ergin Çağrı

机构信息

Department of Health Sciences, İstanbul Kent University, İstanbul, Turkey.

Department of Dermatology, Istanbul Başakşehir Çam and Sakura City Hospital, Başakşehir, Turkey.

出版信息

Indian J Dermatol. 2022 Sep-Oct;67(5):483-487. doi: 10.4103/ijd.ijd_237_22.

Abstract

BACKGROUND

With the Covid-19 pandemic, the use of masks has increased the frequency of 'maskne' cases. Local physiological changes due to the use of mask have caused changes in the presence of yeasts in the environment, such as acne and seborrheic dermatitis.

OBJECTIVES

The aim is to compare the differences of species in the maskne region.

MATERIALS AND METHOD

A total of 408 subjects wearing masks at least 4 h a day for 6 weeks or longer, compromised of 212 acne patients, 72 seborrheic dermatitis sufferers, and 124 healthy volunteers were included in this study. Swab samples were taken for cultures from nasolabial area and their control retro auricular region. The Statistical Package for Social Sciences (SPSS) version 22 was used for the statistical analysis.

RESULTS

species was most frequently found in the nasolabial region of the seborrheic dermatitis group. species were more commonly isolated from the nasolabial region of acne and seborrheic dermatitis patients, compared to the retroauricular region of each patient, than the healthy subjects. The rate of isolated from the nasolabial region was high in all groups, the isolation rate of was low ( < 0.05).

CONCLUSION

As species are more commonly isolated from the nasolabial region of acne and seborrheic dermatitis patients, the increasing numbers of species will trigger inflammation with an antibody reaction against these yeasts. Treatment of resistant acne and seborrheic dermatitis will be facilitated with the knowledge of this inflammation.

摘要

背景

随着新冠疫情的爆发,口罩的使用增加了“口罩痘”病例的发生频率。佩戴口罩引起的局部生理变化导致了环境中酵母菌的存在发生改变,例如痤疮和脂溢性皮炎。

目的

旨在比较“口罩痘”区域内菌种的差异。

材料与方法

本研究共纳入408名每天至少佩戴口罩4小时、持续6周或更长时间的受试者,其中包括212名痤疮患者、72名脂溢性皮炎患者和124名健康志愿者。从鼻唇区域及其对照耳后区域采集拭子样本进行培养。使用社会科学统计软件包(SPSS)22版进行统计分析。

结果

在脂溢性皮炎组的鼻唇区域最常发现某菌种。与每位患者的耳后区域相比,痤疮和脂溢性皮炎患者的鼻唇区域分离出的某菌种比健康受试者更为常见。所有组中从鼻唇区域分离出某菌种的比例较高,某菌种的分离率较低(P<0.05)。

结论

由于痤疮和脂溢性皮炎患者鼻唇区域更常分离出某菌种,某菌种数量的增加将引发针对这些酵母菌的抗体反应炎症。了解这种炎症将有助于治疗难治性痤疮和脂溢性皮炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b0c/9971795/1588b7b47d18/IJD-67-483-g001.jpg

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