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一种新型自组装肽止血凝胶作为内镜超声引导下肝胃造瘘术后瘘出血的抢救治疗。

A novel self-assembling peptide hemostatic gel as rescue therapy for fistula bleeding after endoscopic ultrasound-guided hepaticogastrostomy.

机构信息

Department of Gastroenterology, St. Marianna University School of Medicine, Kawasaki, Japan.

出版信息

J Hepatobiliary Pancreat Sci. 2023 Sep;30(9):e66-e67. doi: 10.1002/jhbp.1326. Epub 2023 Mar 15.

DOI:10.1002/jhbp.1326
PMID:36866588
Abstract

The novel synthetic self-assembling peptide PuraStat has been approved for hemostasis in endoscopic procedures. Nakahara and colleagues describe their application of PuraStat for hemostasis of refractory fistula bleeding after endoscopic ultrasound-guided hepaticogastrostomy. The effective and technically easy procedure is a useful option when hemostasis cannot be achieved by other means.

摘要

新型合成自组装肽 PuraStat 已被批准用于内镜手术中的止血。Nakahara 及其同事描述了他们在经内镜超声引导肝胃造口术后难治性瘘管出血时应用 PuraStat 进行止血的经验。当其他方法无法止血时，这种有效且技术上简单的方法是一种有用的选择。

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引用本文的文献

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Advancement of haemostatic self-assembling peptides in the treatment of gastrointestinal bleeding: What role for PuraStat?止血自组装肽在胃肠道出血治疗中的进展：PuraStat发挥何种作用？
World J Gastrointest Endosc. 2025 May 16;17(5):107183. doi: 10.4253/wjge.v17.i5.107183.
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Efficacy of novel endoscopic hemostatic agent for bleeding control and prevention: Results from a prospective, multicenter national registry.新型内镜止血剂在出血控制与预防方面的疗效：一项前瞻性多中心全国登记研究的结果
Endosc Int Open. 2024 Oct 28;12(10):E1220-E1229. doi: 10.1055/a-2406-7492. eCollection 2024 Oct.