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转移性黑色素瘤患者以机械性膝关节痛为表现的早期分诊 - 病例报告。

Early triage of a patient with metastatic melanoma presenting as mechanical knee pain - a case report.

机构信息

Musculoskeletal Physiotherapy, Refine Health Ltd, Auckland, New Zealand.

Musculoskeletal Physiotherapy, University of Wisconsin- Madison, Madison, WI, USA.

出版信息

J Man Manip Ther. 2023 Aug;31(4):297-303. doi: 10.1080/10669817.2023.2183338. Epub 2023 Mar 3.

DOI:10.1080/10669817.2023.2183338
PMID:36867066
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10324426/
Abstract

Physical therapists (PTs) working in primary care settings commonly encounter mechanical causes of knee pain. Non-mechanical causes of knee pain, such as bone tumors, are rare, and therefore, PTs often have a low index of suspicion regarding sinister pathology. The purpose of this case report is to describe the physical therapist's clinical reasoning process for a 33-year-old female presenting with medial knee pain and a subsequent history of metastatic melanoma. Initially, subjective and objective testing pointed to a mechanical internal derangement of the knee. However, symptom progression and poor treatment responses between physical therapy visits 2 and 3 raised suspicions as to the cause of the knee pain. This prompted an orthopedic referral and medical imaging, revealing a large bone tumor invading the medial femoral condyle, which was further characterized as metastatic melanoma by a specialty oncology team. Further imaging revealed several metastatic subcutaneous, intramuscular and cerebral lesions. This case highlights the importance of the ongoing medical screening process, including the monitoring of symptoms and treatment responses.

摘要

物理治疗师(PT)在初级保健环境中经常遇到膝关节疼痛的机械原因。膝关节疼痛的非机械原因,如骨肿瘤,很少见,因此,PT 通常对恶性病理学的怀疑指数较低。本病例报告的目的是描述一名 33 岁女性出现内侧膝关节疼痛和随后的转移性黑色素瘤病史时,物理治疗师的临床推理过程。最初,主观和客观检查指向膝关节的机械内部紊乱。然而,症状的进展和第 2 次和第 3 次物理治疗就诊之间的治疗反应不佳引起了对膝关节疼痛原因的怀疑。这促使进行了骨科转诊和医学影像学检查,发现了一个大的骨肿瘤侵犯了内侧股骨髁,并进一步由肿瘤学专业团队确定为转移性黑色素瘤。进一步的影像学检查显示了几个转移性皮下、肌肉内和脑内病变。本病例强调了持续医疗筛查过程的重要性,包括症状和治疗反应的监测。

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本文引用的文献

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Global Burden of Cutaneous Melanoma in 2020 and Projections to 2040.2020 年全球皮肤黑色素瘤负担及 2040 年预测。
JAMA Dermatol. 2022 May 1;158(5):495-503. doi: 10.1001/jamadermatol.2022.0160.
2
ACR Appropriateness Criteria® Acute Trauma to the Knee.美国放射学会适宜性标准® 膝关节急性创伤
J Am Coll Radiol. 2020 May;17(5S):S12-S25. doi: 10.1016/j.jacr.2020.01.041.
3
Malignant Bone Tumors of the Knee: How to Identify and Treat.膝关节恶性骨肿瘤:如何识别与治疗
J Knee Surg. 2019 Apr;32(4):305-314. doi: 10.1055/s-0038-1675828. Epub 2018 Nov 16.
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Clinical examination of anterior cruciate ligament rupture: a systematic review and meta-analysis.前交叉韧带断裂的临床检查:一项系统评价与荟萃分析
Acta Orthop Traumatol Turc. 2016;50(1):22-31. doi: 10.3944/AOTT.2016.14.0283.
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Measurement Properties of the Lower Extremity Functional Scale: A Systematic Review.下肢功能量表的测量特性:系统评价。
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Special tests for assessing meniscal tears within the knee: a systematic review and meta-analysis.评估膝关节半月板撕裂的特殊检查:一项系统评价和荟萃分析。
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Knee pain as the reason for encounter in general practice.膝关节疼痛作为全科医疗中就诊的原因。
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8
Pain and nociception: mechanisms of cancer-induced bone pain.疼痛与伤害感受:癌症骨痛的发生机制。
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9
Clinical test for diagnosis of patellofemoral pain syndrome: Systematic review with meta-analysis.髌股疼痛综合征的临床诊断测试:系统评价与荟萃分析。
Phys Ther Sport. 2013 Feb;14(1):54-9. doi: 10.1016/j.ptsp.2012.11.003. Epub 2012 Dec 8.
10
Metastatic behavior in melanoma: timing, pattern, survival, and influencing factors.黑色素瘤的转移行为:时间、模式、生存和影响因素。
J Oncol. 2012;2012:647684. doi: 10.1155/2012/647684. Epub 2012 Jun 27.