• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

采用中央象限切除术及即刻乳头乳晕重建术治疗的中央型乳腺癌:一项队列研究。

Centrally located breast carcinomas treated with central quadrantectomy and immediate nipple-areola reconstruction: a cohort study.

作者信息

Fernando Hernanz, Noelia González, Maria Esteban, Pedro Muñoz

机构信息

Breast Unit, Hospital Valdecilla, University of Cantabria, Avda. Valdecilla Sn, 39008, Santander, Cantabria, Spain.

Servicio Cántabro de Salud (SCS), Instituto de Investigación Sanitaria Valdecilla (IDIVAL), Santander, Cantabria, Spain.

出版信息

Breast Cancer. 2023 Jul;30(4):552-558. doi: 10.1007/s12282-023-01445-6. Epub 2023 Mar 3.

DOI:10.1007/s12282-023-01445-6
PMID:36867348
Abstract

BACKGROUND

Mastectomy has often been cited as the favoured option for centrally located breast tumours because lumpectomies or quadrantectomies that remove the nipple-areola complex often result in poor cosmesis. Currently, breast-conserving treatment is a preferred treatment for centrally located breast tumours, but this approach requires oncoplastic breast technique to avoid aesthetic sequels. This article describes the use of breast reduction techniques with immediate nipple-areola complex reconstruction (utilised to treat breast cancer) for centrally sited breast tumours PATIENTS: Ten patients suffering from a centrally located breast carcinoma were treated at our breast unit over a period of 16 years (2006-2022). Oncologic and patient-reported outcomes were updated revising electronic reports and surveying with BREAST-Q module Breast conserving therapy (version 2, Spanish) postoperative scales.

RESULTS

Excision margins were complete in all cases. There have been no postoperative complications, all patients are alive and no cases of recurrence after 84.8 months of mean follow-up. Patients score the domain satisfaction with breast: mean 61.7 (Standard deviation 12.5) out of 100.

CONCLUSIONS

Breast reduction mammaplasty with immediate nipple-areola complex reconstruction allows surgeons to carry out a central quadrantectomy to treat centrally located breast carcinoma with good oncologic and cosmetic outcome.

摘要

背景

乳房切除术常被视为治疗中央型乳腺肿瘤的首选方案,因为切除乳头乳晕复合体的肿块切除术或象限切除术往往会导致美容效果不佳。目前,保乳治疗是中央型乳腺肿瘤的首选治疗方法,但这种方法需要肿瘤整形乳房技术来避免美学后遗症。本文描述了采用乳房缩小技术并立即进行乳头乳晕复合体重建(用于治疗乳腺癌)来治疗中央型乳腺肿瘤。

患者

在16年期间(2006 - 2022年),我们乳腺科对10例患有中央型乳腺癌的患者进行了治疗。通过修订电子报告并使用BREAST - Q模块乳房保乳治疗(第2版,西班牙语)术后量表进行调查,更新了肿瘤学和患者报告的结果。

结果

所有病例切缘均为阴性。术后无并发症发生,所有患者均存活,平均随访84.8个月后无复发病例。患者对乳房领域的满意度评分:平均为61.7(标准差12.5),满分100分。

结论

采用乳房缩小整形术并立即进行乳头乳晕复合体重建,外科医生能够实施中央象限切除术来治疗中央型乳腺癌,获得良好的肿瘤学和美容效果。

相似文献

1
Centrally located breast carcinomas treated with central quadrantectomy and immediate nipple-areola reconstruction: a cohort study.采用中央象限切除术及即刻乳头乳晕重建术治疗的中央型乳腺癌:一项队列研究。
Breast Cancer. 2023 Jul;30(4):552-558. doi: 10.1007/s12282-023-01445-6. Epub 2023 Mar 3.
2
A comparative study between central quadrantectomy and nipple resection with areola preservation Versus Grisotti flap mammoplasty in central breast lesions extending to nipple: a randomized clinical trial.中央象限切除术与保留乳晕的乳头切除术对比Grisotti皮瓣乳房成形术治疗累及乳头的中央型乳腺病变:一项随机临床试验
J Egypt Natl Canc Inst. 2025 Jan 20;37(1):3. doi: 10.1186/s43046-024-00253-z.
3
Oncoplastic breast-conserving surgery for women with primary breast cancer.原发性乳腺癌患者的肿瘤整形保乳手术。
Cochrane Database Syst Rev. 2021 Oct 29;10(10):CD013658. doi: 10.1002/14651858.CD013658.pub2.
4
7-step endoscopic nipple-sparing mastectomy with implant-based breast reconstruction: nipple sensation preservation and low complications.基于植入物乳房重建的七步内镜保留乳头乳房切除术:乳头感觉保留及低并发症发生率
World J Surg Oncol. 2025 Jul 22;23(1):292. doi: 10.1186/s12957-025-03935-7.
5
Nipple- and areola-sparing mastectomy for the treatment of breast cancer.保留乳头乳晕的乳房切除术治疗乳腺癌。
Cochrane Database Syst Rev. 2016 Nov 29;11(11):CD008932. doi: 10.1002/14651858.CD008932.pub3.
6
Comparative Outcome Study of Gynecomastia Surgery and Gender-Affirming Mastectomy With 100% Nipple Preservation.保留100%乳头的男性乳房肥大症手术与性别确认乳房切除术的比较结果研究
Ann Plast Surg. 2025 Jul 1;95(1):e1-e17. doi: 10.1097/SAP.0000000000004308. Epub 2025 Feb 17.
7
Implants versus autologous tissue flaps for breast reconstruction following mastectomy.乳房切除术乳房再造中假体与自体组织皮瓣的比较。
Cochrane Database Syst Rev. 2024 Oct 31;10(10):CD013821. doi: 10.1002/14651858.CD013821.pub2.
8
Introducing an oncoplastic approach for centrally located breast cancer patients.为中心型乳腺癌患者引入肿瘤整形方法。
World J Surg Oncol. 2025 Jun 23;23(1):249. doi: 10.1186/s12957-025-03848-5.
9
Outcomes Following Oncoplastic Reduction Mammoplasty: A Systematic Review.肿瘤整形缩小乳房成形术后的结局:一项系统评价
Ann Plast Surg. 2016 May;76 Suppl 3:S222-6. doi: 10.1097/SAP.0000000000000720.
10
Interventions for treating painful nipples among breastfeeding women.母乳喂养女性乳头疼痛的治疗干预措施。
Cochrane Database Syst Rev. 2014 Dec 15;2014(12):CD007366. doi: 10.1002/14651858.CD007366.pub2.

本文引用的文献

1
Survival Outcomes of Breast-Conserving Therapy versus Mastectomy in Early-Stage Breast Cancer, Including Centrally Located Breast Cancer: A SEER-Based Study.早期乳腺癌保乳治疗与乳房切除术的生存结局比较,包括中央型乳腺癌:基于 SEER 的研究。
Breast J. 2022 Aug 27;2022:5325556. doi: 10.1155/2022/5325556. eCollection 2022.
2
Breast-conserving in centrally located breast cancer patients confirmed safe by SEER based study.基于监测、流行病学和最终结果(SEER)数据库的研究证实,保乳手术对于中央型乳腺癌患者是安全的。
Gland Surg. 2022 Jan;11(1):226-235. doi: 10.21037/gs-21-914.
3
Breast-Conserving Surgery is Oncologically Safe for Well-Selected, Centrally Located Breast Cancer.
对于精心挑选的、位于乳腺中央部位的乳腺癌患者,保乳手术在肿瘤学上是安全的。
Ann Surg Oncol. 2021 Jan;28(1):330-339. doi: 10.1245/s10434-020-08793-z. Epub 2020 Jul 7.
4
Breast conserving therapy is associated with improved overall survival compared to mastectomy in early-stage, lymph node-negative breast cancer.保乳治疗与早期、淋巴结阴性乳腺癌的乳房切除术相比,与改善总生存相关。
Radiother Oncol. 2020 Jan;142:186-194. doi: 10.1016/j.radonc.2019.09.018. Epub 2019 Oct 12.
5
Oncoplastic central quadrantectomies.肿瘤整形中央象限切除术。
Gland Surg. 2016 Aug;5(4):422-6. doi: 10.21037/gs.2016.04.01.
6
Central quadrantectomy with resection of the nipple-areola complex compared with mastectomy in patients with retroareolar breast cancer.乳晕后乳腺癌患者行中央象限切除术加乳头乳晕复合体切除与乳房切除术的比较
Breast J. 2007 Nov-Dec;13(6):557-63. doi: 10.1111/j.1524-4741.2007.00492.x.
7
Breast conserving surgery for breast cancer involving the nipple.保留乳头的乳腺癌保乳手术。
Breast. 2008 Feb;17(1):107-10. doi: 10.1016/j.breast.2007.07.036. Epub 2007 Sep 24.
8
Immediate reconstruction of the nipple/areola complex in oncoplastic surgery after central quadrantectomy.中央象限切除术后肿瘤整形手术中乳头/乳晕复合体的即刻重建。
Ann Plast Surg. 2006 Dec;57(6):611-5. doi: 10.1097/01.sap.0000235444.51056.31.
9
Therapeutic mammaplasty for centrally located breast tumors.
Plast Reconstr Surg. 2006 Feb;117(2):366-73. doi: 10.1097/01.prs.0000200874.31320.c2.