Schönfelder M
Klinik für Chirurgie im Bereich Medizin, Karl-Marx-Universität Leipzig.
Zentralbl Chir. 1987;112(18):1150-4.
In vitro tests applied to cell cultures of metastasised mammary carcinomas revealed high hormonal independence versus testosterone and/or oestradiol, prednisone, progesterone, and prolactin, and in some cases tumour growth was even stimulated by those hormones. Hormonal therapy on the basis of the in vitro parameters was applied to 62 patients with metastatic mammary carcinoma. In vitro findings were closely correlated to in vivo results.
对转移性乳腺癌细胞培养物进行的体外试验显示，其对睾酮和/或雌二醇、泼尼松、孕酮和催乳素具有高度激素独立性，在某些情况下，这些激素甚至会刺激肿瘤生长。基于体外参数对62例转移性乳腺癌患者进行了激素治疗。体外研究结果与体内结果密切相关。
