Department of Surgery No.1, Bukovinian State Medical University, West Vascular Center, Chernivtsi, Ukraine.
West Vascular Center, Chernivtsi, Ukraine.
J Med Life. 2023 Jan;16(1):35-41. doi: 10.25122/jml-2022-0187.
Thyroid nodules are common, occurring in 50-60% of healthy patients. Currently, there are no effective conservative treatment options for nodular goiter, and surgery can have limitations and potential complications. The purpose of this study was to evaluate the efficacy, tolerability, and long-term results of using sclerotherapy and laser-induced interstitial thermotherapy (LITT) to treat benign thyroid nodules. A retrospective analysis was conducted on 456 patients with benign nodular goiter who received LITT. The volume of the nodular goiter was measured at 1, 3, 6, and 12 months post-treatment, and a repeated fine needle aspiration (FNA) with the cytological examination was performed to verify the structure of the nodular goiter in the long term. The results showed that LITT was an effective method for treating nodular mass (nodules), as evidenced by a decrease in the volume of NG by 51-85% after 6-12 months. FNA results 2-3 years after LITT showed no thyrocytes, only connective tissue, indicating the efficacy of LITT for benign thyroid nodules. LITT is highly effective in most cases, often resulting in the disappearance or significant decrease in nodular formations.
甲状腺结节很常见,在 50%-60%的健康患者中发生。目前,结节性甲状腺肿没有有效的保守治疗选择,手术可能有局限性和潜在的并发症。本研究旨在评估硬化疗法和激光诱导间质热疗(LITT)治疗良性甲状腺结节的疗效、耐受性和长期结果。对 456 例接受 LITT 治疗的良性结节性甲状腺肿患者进行了回顾性分析。在治疗后 1、3、6 和 12 个月测量结节性甲状腺肿的体积,并进行重复的细针抽吸(FNA)和细胞学检查,以长期验证结节性甲状腺肿的结构。结果表明,LITT 是治疗结节性肿块(结节)的有效方法,因为在 6-12 个月后,NG 体积减少了 51%-85%。LITT 后 2-3 年的 FNA 结果显示没有甲状腺细胞,只有结缔组织,表明 LITT 对良性甲状腺结节有效。LITT 在大多数情况下非常有效,通常导致结节形成的消失或显著减少。