Claus D, Hilz M J, Hummer I, Neundörfer B
Department of Neurology, University Erlangen, Nuremberg, West Germany.
Acta Neurol Scand. 1987 Oct;76(4):288-96. doi: 10.1111/j.1600-0404.1987.tb03583.x.
Thermal tests were performed in 117 healthy subjects on the face, wrist and leg; 32 were tested on the legs with different rates of cooling and warming. Additionally 2 groups of diabetics (37 patients) were tested. Thermotesting was most sensitive on the legs using a rate of temperature change of 2.5-2.8 oC/s. Warm and cold perception should be tested separately. Cold perception testing is most sensitive. Combined tests of warm and cold thresholds as well as the testing of cool pain and heat pain do not improve results. Abnormal cold perception may be an early indicator of diabetic small fibre polyneuropathy, leading to cold trauma and ulcers on the feet.
对117名健康受试者的面部、手腕和腿部进行了热测试；32人在腿部以不同的冷却和升温速率进行了测试。另外还对两组糖尿病患者（37名患者）进行了测试。使用2.5 - 2.8℃/秒的温度变化速率时，腿部的热测试最为敏感。冷热感知应分别进行测试。冷感知测试最为敏感。冷热阈值的联合测试以及冷痛和热痛测试并不能改善测试结果。冷感知异常可能是糖尿病小纤维多神经病变的早期指标，会导致足部冷伤和溃疡。
