He Yu, Qian Liyuan, Chen Lang, Liu Yang, Wen Yanguang, Cao Peiguo
Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.
Department of Breast and Thyroid Surgery, Third Xiangya Hospital, Central South University, Changsha, China.
Front Surg. 2023 Feb 17;9:966792. doi: 10.3389/fsurg.2022.966792. eCollection 2022.
Primary breast angiosarcoma (PBA) is a rare sarcoma, accounting for only 0.04% of all breast malignancies, with a difficult diagnosis and a poor prognosis. Mastectomy is the standard treatment, and the role of adjuvant treatment (chemotherapy and/or radiotherapy following surgery) remains uncertain with very few studies.
We report the case of a 17-year-old female patient who presented with a right breast lump that had rapidly increased in size and was hemorrhaging. She was diagnosed with breast angiosarcoma by needle biopsy and pathological evaluation. However, the mass showed a quick tendency to bleed during biopsies. After that, we performed angiography and tumor vascular embolization. The patient underwent a mastectomy followed by adjuvant chemotherapy.
Tumor vascular embolization reduced the surgical risk of PBA with hemorrhage complications. Postoperative therapeutic roles still need further exploration and verification.
原发性乳腺血管肉瘤(PBA)是一种罕见的肉瘤,仅占所有乳腺恶性肿瘤的0.04%,诊断困难且预后较差。乳房切除术是标准治疗方法,而辅助治疗(手术后的化疗和/或放疗)的作用仍不明确,相关研究极少。
我们报告一例17岁女性患者,其右乳出现一个迅速增大且伴有出血的肿块。经针吸活检和病理评估,她被诊断为乳腺血管肉瘤。然而,在活检过程中肿块显示出快速出血的倾向。之后,我们进行了血管造影和肿瘤血管栓塞。患者接受了乳房切除术,随后进行辅助化疗。
肿瘤血管栓塞降低了PBA伴出血并发症的手术风险。术后治疗作用仍需进一步探索和验证。