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误诊为甲状腺恶性肿瘤的朗格汉斯细胞组织细胞增多症:一例报告。

Langerhans cell histiocytosis misdiagnosed as thyroid malignancy: A case report.

作者信息

Shi Jing-Jing, Peng You, Zhang Yu, Zhou Li, Pan Gang

机构信息

Department of Oncological Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China.

出版信息

World J Clin Cases. 2023 Feb 16;11(5):1152-1157. doi: 10.12998/wjcc.v11.i5.1152.

Abstract

BACKGROUND

The incidence of Langerhans cell histiocytosis (LCH) is low, and involvement of the thyroid is even rarer, which results in high missed diagnosis or misdiagnosis rates.

CASE SUMMARY

We report a young woman with a thyroid nodule. Thyroid malignancy was suggested by fine needle aspiration, but she was eventually diagnosed with multisystem LCH, thus avoiding thyroidectomy.

CONCLUSION

The clinical manifestations of LCH involving the thyroid are atypical, and the diagnosis depends on pathology. Surgery is the main method for treating primary thyroid LCH, while chemotherapy is the main treatment method for multisystem LCH.

摘要

背景

朗格汉斯细胞组织细胞增多症(LCH)的发病率较低,甲状腺受累更为罕见,这导致漏诊或误诊率较高。

病例摘要

我们报告一名患有甲状腺结节的年轻女性。细针穿刺提示甲状腺恶性肿瘤,但她最终被诊断为多系统LCH,从而避免了甲状腺切除术。

结论

LCH累及甲状腺的临床表现不典型,诊断依赖于病理检查。手术是治疗原发性甲状腺LCH的主要方法,而化疗是多系统LCH的主要治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6b5/9979281/9577d6171c67/WJCC-11-1152-g001.jpg

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