Shi Jing-Jing, Peng You, Zhang Yu, Zhou Li, Pan Gang
Department of Oncological Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China.
World J Clin Cases. 2023 Feb 16;11(5):1152-1157. doi: 10.12998/wjcc.v11.i5.1152.
The incidence of Langerhans cell histiocytosis (LCH) is low, and involvement of the thyroid is even rarer, which results in high missed diagnosis or misdiagnosis rates.
We report a young woman with a thyroid nodule. Thyroid malignancy was suggested by fine needle aspiration, but she was eventually diagnosed with multisystem LCH, thus avoiding thyroidectomy.
The clinical manifestations of LCH involving the thyroid are atypical, and the diagnosis depends on pathology. Surgery is the main method for treating primary thyroid LCH, while chemotherapy is the main treatment method for multisystem LCH.
朗格汉斯细胞组织细胞增多症（LCH）的发病率较低，甲状腺受累更为罕见，这导致漏诊或误诊率较高。
我们报告一名患有甲状腺结节的年轻女性。细针穿刺提示甲状腺恶性肿瘤，但她最终被诊断为多系统LCH，从而避免了甲状腺切除术。
LCH累及甲状腺的临床表现不典型，诊断依赖于病理检查。手术是治疗原发性甲状腺LCH的主要方法，而化疗是多系统LCH的主要治疗方法。
