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口腔颌面外科医生对基底细胞痣综合征的观点——两例报告

Oral and Maxillofacial Surgeon's Perspective on Gorlin-Goltz Syndrome - A Report of Two Cases.

作者信息

Wadde Kavita Ramesh, Ghodke Monali N, Chowdhar Asha S, Nadkarni Shambhavi P, Venkatakrishnan Lakshmi, Sarda Ashish

机构信息

Department of Oral and Maxillofacial Surgery, Government Dental College and Hospital, Mumbai, Maharashtra, India.

出版信息

Ann Maxillofac Surg. 2022 Jul-Dec;12(2):248-251. doi: 10.4103/ams.ams_235_21. Epub 2023 Jan 10.

Abstract

RATIONALE

Gorlin-Goltz syndrome (GGS) is an autosomal dominant disorder and is associated with multisystem involvement, multiple cysts, neoplasms and other developmental anomalies. The purpose of the study was to highlight the incidental findings of GGS and to lay emphasis on its early diagnosis.

PATIENT CONCERNS

Two patients complaining of pain, swelling and at times pus discharge from the oral cavity were reported with a coincidental finding of odontogenic keratocysts and positive family history.

DIAGNOSIS

Upon thorough examination, a diagnosis of GGS was made.

TREATMENT

The patients were managed by enucleation and chemical cauterisation using Carnoy's solution and were maintained on follow-up semi-annually.

OUTCOMES

Both patients showed no signs of recurrence post six months follow-up.

LESSONS

The role of an oral and maxillofacial surgeon is of utmost importance in the early diagnosis of this syndrome to render good quality of life to these patients.

摘要

理论依据

戈林-戈尔茨综合征(GGS)是一种常染色体显性疾病,与多系统受累、多发囊肿、肿瘤及其他发育异常有关。本研究的目的是强调GGS的偶然发现,并着重于其早期诊断。

患者情况

报告了两名患者,他们抱怨口腔疼痛、肿胀,有时还有脓液排出,同时偶然发现牙源性角化囊肿且有阳性家族史。

诊断

经过全面检查,确诊为GGS。

治疗

对患者进行了囊肿摘除术,并使用卡诺伊溶液进行化学烧灼,每半年进行一次随访。

结果

在六个月的随访中,两名患者均未出现复发迹象。

经验教训

口腔颌面外科医生在该综合征的早期诊断中起着至关重要的作用,可为这些患者带来良好的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd7c/9976865/1ea45b159be9/AMS-12-248-g001.jpg

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