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距骨巨细胞瘤——病例报告

Giant Cell Tumor of Talus - A Case Report.

作者信息

Panda Siddharth, Rana Rajesh, Sekhar Siddharth, Behera Sudarsan

机构信息

Department of Orthopaedics, Institute of Medical Sciences SUM Hospital and Medical College, Bhubaneswar, Odisha, India.

出版信息

J Orthop Case Rep. 2022 Oct;12(10):87-90. doi: 10.13107/jocr.2022.v12.i10.3380.

DOI:10.13107/jocr.2022.v12.i10.3380
PMID:36874902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9983387/
Abstract

INTRODUCTION

A giant cell tumor (GCT) is a benign tumor of bones which commonly arises from epiphysis of long bones. The tumor is locally aggressive and rarely metastasizes to the lungs. GCT of small bones of the foot and ankle is very rare. The GCT of the talus is very rare, and only a few case reports and series are described in the literature. In general, the GCT is monostotic, and few incidences of multicentricity have been described in the foot and ankle bones literature. Here are the findings of our case GCT of talus and reviews of earlier literature.

CASE REPORT

We present a case of a GCT of the talus in a 22-year-old female. Patient presented with pain in ankle with mild swelling and tenderness at ankle. Radiograph and Computer tomography scan conformed an eccentric osteolytic lesion on anterolateral part of talus body. Magnetic resonance imaging showed no extra osseous extension or articular surface breach. Biopsy conformed the lesion to be giant cell tumor. The tumor was reated with curettage and bone cement filling.

CONCLUSION

Giant cell tumor of talus is extremely rare and presentation of these tumor may change. Curettage and bone cementing are an effective method of treatment. It gives early weight bearing and rehabilitation.

摘要

引言

骨巨细胞瘤是一种常见于长骨干骺端的良性骨肿瘤。该肿瘤具有局部侵袭性,很少转移至肺部。足踝部小骨的骨巨细胞瘤非常罕见。距骨的骨巨细胞瘤极为罕见,文献中仅有少数病例报告和系列报道。一般来说,骨巨细胞瘤为单发性,足踝部骨骼文献中关于多中心性的发生率描述较少。以下是我们这例距骨骨巨细胞瘤的病例报告及对早期文献的综述。

病例报告

我们报告一例22岁女性距骨骨巨细胞瘤。患者表现为踝关节疼痛,伴有轻度肿胀和压痛。X线片和计算机断层扫描显示距骨体前外侧有一偏心性溶骨性病变。磁共振成像显示无骨外扩展或关节面破坏。活检证实病变为骨巨细胞瘤。该肿瘤采用刮除术和骨水泥填充治疗。

结论

距骨骨巨细胞瘤极为罕见,这些肿瘤的表现可能会有所不同。刮除术和骨水泥填充是一种有效的治疗方法。它能使患者早期负重并进行康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c1/9983387/4c09eb0e33e9/JOCR-12-87-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c1/9983387/de97d7d50356/JOCR-12-87-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c1/9983387/25a3ef7caca5/JOCR-12-87-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c1/9983387/2c5b0279969e/JOCR-12-87-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c1/9983387/49e5bd890355/JOCR-12-87-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c1/9983387/4c09eb0e33e9/JOCR-12-87-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c1/9983387/de97d7d50356/JOCR-12-87-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c1/9983387/25a3ef7caca5/JOCR-12-87-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c1/9983387/2c5b0279969e/JOCR-12-87-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c1/9983387/49e5bd890355/JOCR-12-87-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0c1/9983387/4c09eb0e33e9/JOCR-12-87-g005.jpg

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本文引用的文献

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Use of cement combined grafting in upper and lower extremity benign bone tumors.骨水泥联合植骨在上下肢良性骨肿瘤中的应用
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Giant cell tumor of the talus: A case report.距骨巨细胞瘤:一例报告。
Radiol Case Rep. 2020 Apr 22;15(7):825-831. doi: 10.1016/j.radcr.2020.03.016. eCollection 2020 Jul.
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Locally Aggressive Giant Cell Tumor of Bone With Pulmonary Distant Metastasis and Extrapulmonary Seeding in Pregnancy.骨巨细胞瘤局部侵袭性,伴妊娠时肺部远处转移和肺外播散。
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