Shenzhen Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine, Shenzhen, Guangdong, China.
Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, China.
Front Public Health. 2023 Feb 17;11:1094062. doi: 10.3389/fpubh.2023.1094062. eCollection 2023.
The prevalence of obesity is on the rise and is connected to numerous factors. However, the relationship between obesity and nickel has never been investigated. Our study aimed to explore the association between urinary nickel and obesity Status in adults.
From the 2017-2018 National Health and Nutrition Examination Surveys (NHANES), 1,705 participants ≥18 years of age were enrolled. To explore further the relationship among urinary nickel, body mass index (BMI), and waist circumference(WC), Weighted multivariate linear regression analyses and further subgroup analyzes were conducted.
Urinary nickel does not correlate with BMI level but positively correlates with WC. In the subgroup analyzed according to sex, Urinary nickel has a positive correlation with BMI and WC in males but has a negative correlation in females. Secondary stratification analysis according to sex and race, Urinary nickel positively correlates with BMI in White males. It also positively correlates with WC in both White and Black males.
A correlation was found between urinary nickel levels and BMI and WC in adult males. Adult men, especially those already obese, may need to reduce nickel exposure.
肥胖的患病率呈上升趋势，与许多因素有关。然而，肥胖与镍之间的关系从未被研究过。我们的研究旨在探讨成年人尿镍与肥胖状况之间的关系。
从 2017-2018 年全国健康与营养调查（NHANES）中，纳入了 1705 名年龄≥18 岁的参与者。为了进一步探讨尿镍、体重指数（BMI）和腰围（WC）之间的关系，进行了加权多变量线性回归分析和进一步的亚组分析。
尿镍与 BMI 水平无关，但与 WC 呈正相关。根据性别进行的亚组分析显示，尿镍与男性的 BMI 和 WC 呈正相关，但在女性中呈负相关。根据性别和种族进行的二次分层分析显示，尿镍与白种男性的 BMI 呈正相关。它还与白人和黑种男性的 WC 呈正相关。
在成年男性中，尿镍水平与 BMI 和 WC 之间存在相关性。成年男性，尤其是那些已经肥胖的男性，可能需要减少镍暴露。
