Gulumsek Erdinc, Ozturk Dilan Damla, Ozturk Huseyin Ali, Saler Tayyibe, Erdogan Kivilcim Eren, Bashir Ahmed Muhammad, Sumbul Hilmi Erdem
Department of Gastroenterology, University of Health Sciences-Adana Health Practice and Research Center, Adana, Turkey.
Department of Internal Medicine, University of Health Sciences-Adana Health Practice and Research Center, Adana, Turkey.
Case Rep Infect Dis. 2023 Feb 22;2023:5122228. doi: 10.1155/2023/5122228. eCollection 2023.
Nephrotic syndrome progresses with various metabolic disturbances, such as proteinuria over 3.5 grams in 24 hours, hypoalbuminemia, and hypercoagulability. Patients usually complain about diffuse edema throughout the body, which is secondary to hypoalbuminemia. It has many primary and secondary causes. Patients may require a renal biopsy to confirm the diagnosis. Besides, many secondary causes of nephrotic syndrome should be examined and excluded. Although many vaccines were developed due to the COVID-19, many side effects are still reported because of the Pfizer-BioNTech COVID-19 vaccine (COVID-19 mRNA and BNT162b2), which is widely used in Turkey. This study examines a case of nephrotic syndrome with acute renal injury after Pfizer-BioNTech vaccine.
肾病综合征会伴随各种代谢紊乱而进展，如24小时蛋白尿超过3.5克、低白蛋白血症和高凝状态。患者通常会抱怨全身弥漫性水肿，这是低白蛋白血症的继发症状。它有许多原发性和继发性病因。患者可能需要进行肾活检以确诊。此外，应检查并排除肾病综合征的许多继发性病因。尽管由于新冠疫情研发了许多疫苗，但广泛应用于土耳其的辉瑞 - 生物科技新冠疫苗（新冠mRNA疫苗和BNT162b2）仍报告了许多副作用。本研究探讨了一例接种辉瑞 - 生物科技疫苗后发生急性肾损伤的肾病综合征病例。
