Zhou Shengluan, Sheng Chenyi, Hu Ping, Ni Xuejun, Xu Xiaoping, Song Qian, Jiang Xiaoxiao, Zhao Hui, Chen Xiaoyang
Department of Medical Ultrasound, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, China.
Department of Thyroid and Breast Surgery, Affiliated Hospital of Nantong University, Nantong, China.
Breast Care (Basel). 2023 Feb;18(1):1-11. doi: 10.1159/000527128. Epub 2022 Nov 3.
This study investigated the feasibility of ultrasound (US)-guided microwave ablation (MWA) as a treatment for nonpuerperal mastitis (NPM).
Fifty-three patients with NPM diagnosed by biopsy and treated with US-guided MWA at the Affiliated Hospital of Nantong University between September 2020 and February 2022 were classified according to whether they underwent MWA alone ( = 29) or MWA with incision and drainage ( = 24). Patients were followed up by interviews, physical and US examinations, and evaluation of breast skin at 1 week and 1, 2, and 3 months after treatment. Data from these patients were prospectively collected and retrospectively analyzed.
The overall mean patient age was 34.42 ± 9.20 years. The groups differed significantly by age, involved quadrants, and the initial maximum diameter of lesions. In the MWA group, the cure rate was 34.48%, and the apparent efficiency rate was 65.52%. In the MWA with incision and drainage, the apparent efficiency rate was 91.66%, and the effective rate was 4.17%. The excellent rate for breast aesthetics in the MWA group was 79.31%, and the good rate was 20.69%. The excellent rate in the MWA with incision and drainage group was 45.83%, the good rate was 41.67%, and the qualified rate was 12.5%. The mean maximum diameter of lesions in the two groups decreased significantly.
For NPM with small lesions in a single quadrant, MWA therapy is a direct and effective method. For larger lesions involving two or more quadrants, the combined treatment of MWA with incision and drainage showed significant improvement in a short period. MWA treatment of NPM has importance for further research and clinical applications.
本研究探讨了超声（US）引导下微波消融（MWA）治疗非产褥期乳腺炎（NPM）的可行性。
2020年9月至2022年2月期间，南通大学附属医院对53例经活检确诊并接受超声引导下微波消融治疗的非产褥期乳腺炎患者，根据是否单纯接受微波消融治疗（n = 29）或微波消融联合切开引流治疗（n = 24）进行分类。治疗后1周、1、2和3个月，通过访谈、体格检查、超声检查以及评估乳房皮肤情况对患者进行随访。前瞻性收集这些患者的数据并进行回顾性分析。
患者的总体平均年龄为34.42±9.20岁。两组在年龄、受累象限以及病变初始最大直径方面存在显著差异。微波消融组的治愈率为34.48%，显效率为65.52%。微波消融联合切开引流组的显效率为91.66%，有效率为4.17%。微波消融组乳房美学优良率为79.31%，良好率为20.69%。微波消融联合切开引流组优良率为45.83%，良好率为41.67%，合格 率为12.5%。两组病变的平均最大直径均显著减小。
对于单象限小病变的非产褥期乳腺炎，微波消融治疗是一种直接有效的方法。对于累及两个或更多象限的较大病变，微波消融联合切开引流的综合治疗在短期内显示出显著改善。微波消融治疗非产褥期乳腺炎对进一步研究和临床应用具有重要意义。
