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单形上皮样肠道T细胞淋巴瘤患者单纯姑息性放射治疗而非化疗:一例报告

Palliative Radiation Therapy without Chemotherapy for a Patient with Monomorphic Epitheliotropic Intestinal T Cell Lymphoma: A Case Report.

作者信息

Kusada Takeaki, Ariga Takuro, Kina Kaori, Okubo Yohei, Kiyuna Masaya, Kadekaru Tsutomu, Tomiyama Takeshi, Kamiya Hisashi, Gibo Masaki, Nishie Akihiro

机构信息

Department of Radiology, Okinawa Red Cross Hospital, Naha, Japan.

Department of Radiology, Graduate School of Medicine, University of the Ryukyus, Nishihara, Japan.

出版信息

Palliat Med Rep. 2022 Nov 3;3(1):272-278. doi: 10.1089/pmr.2022.0011. eCollection 2022.

Abstract

Monomorphic epitheliotropic intestinal T cell lymphoma (MEITL), which used to be known as type 2 enteropathy-associated T cell lymphoma, is a rare lymphoma and is generally treated with chemotherapy. However, the MEITL prognosis is poor, and intestinal lymphoma including MEITL has the risk of bowel perforation not only at presentation but also during chemotherapy. A 67-year-old man was diagnosed with MEITL after presenting in our emergency room with bowel perforation. He and his family did not opt for the administration of anticancer drugs because of the risk of bowel perforation. However, they wanted the patient to receive palliative radiation therapy without chemotherapy. This treatment shrunk the tumor size without causing severe complications or decline in the quality of life, until he accidentally died due to traumatic intracranial hematoma. Considering the potential efficacy and safety of this treatment, it should be studied in more patients with MEITL.

摘要

单形性上皮趋化性肠道T细胞淋巴瘤(MEITL),过去被称为2型肠病相关T细胞淋巴瘤,是一种罕见的淋巴瘤,通常采用化疗进行治疗。然而,MEITL的预后较差,包括MEITL在内的肠道淋巴瘤不仅在就诊时而且在化疗期间都有肠穿孔的风险。一名67岁男性因肠穿孔在我们的急诊室就诊后被诊断为MEITL。由于存在肠穿孔风险,他和他的家人没有选择使用抗癌药物。然而,他们希望患者接受不进行化疗的姑息性放射治疗。这种治疗缩小了肿瘤大小,没有引起严重并发症或生活质量下降,直到他因外伤性颅内血肿意外死亡。考虑到这种治疗的潜在疗效和安全性,应该在更多的MEITL患者中进行研究。

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