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肥胖和非肥胖学龄儿童术前饮用清液后的胃排空时间:一项前瞻性观察研究。

Gastric emptying times of obese and non-obese school-aged children after preoperative clear fluid intake: A prospective observational study.

机构信息

Department of Anaesthesiology and Reanimation, Karamanoglu Mehmetbey University, School of Medicine, Karaman, Turkey.

Department of Anaesthesiology and Reanimation, Karaman Training and Research Hospital, Karaman, Turkey.

出版信息

Paediatr Anaesth. 2023 Jul;33(7):539-545. doi: 10.1111/pan.14658. Epub 2023 Mar 16.

Abstract

BACKGROUND

Liberal fasting regimens, which support clear fluid intake up to 1 h before surgery in children scheduled for elective surgery, are taking their place in guidelines. However, because of the lack of publications that investigate the gastric emptying time in preoperative obese children, the practice of 1-hour clear fluid fasting in obese children remained at the level of recommendation with weak evidence.

AIMS

The primary aim was to investigate whether there is a difference in gastric emptying times between obese and non- obese children after preoperative intake of 3 mL/kg clear liquid containing 5% dextrose by using ultrasound.

METHODS

A total of 70 children were included in the study in two groups, 35 obese and 35 non-obese, aged 6-14 years, who were scheduled for elective surgery. The baseline antral cross-sectional area measurements of the children in the groups were made using ultrasound. 3 mL/kg 5% dextrose was consumed. Ultrasound was repeated immediately after fluid intake and every 5 min until the antral cross-sectional area was at the baseline level.

RESULTS

The difference in median (IQR [range]) gastric emptying times (minutes) of non-obese {35 [30.0-45.0 (20-60)]} and obese children {35 [30.0-40.0 (25-60)]} were not statistically significant (median of differences 0.0, 95% CI -5.0 to 5.0; p = .563). The antral cross-sectional area and weight-adjusted gastric volumes returned to the baseline level within 60 min after the intake of clear liquid with 3 mL/kg 5% dextrose in all children in both groups.

CONCLUSIONS

Obese and non-obese children have similar gastric emptying times, and these groups can be offered clear fluids containing 3 mL/kg 5% dextrose 1 h before the surgery.

摘要

背景

在择期手术的儿童中,支持术前 1 小时内饮用清亮液体的宽松禁食方案正在替代指南中的传统禁食方案。然而,由于缺乏研究肥胖儿童胃排空时间的出版物,肥胖儿童术前 1 小时内饮用清亮液体的做法仍然停留在推荐水平,证据薄弱。

目的

本研究旨在通过超声检查评估肥胖儿童与非肥胖儿童在术前饮用 3ml/kg 含 5%葡萄糖的清亮液体后胃排空时间是否存在差异。

方法

本研究共纳入 70 名儿童,分为肥胖组和非肥胖组,每组 35 名,年龄 6-14 岁,均拟行择期手术。使用超声测量两组儿童的基础胃窦横截面积。儿童饮用 3ml/kg 5%葡萄糖溶液。饮用后立即重复超声检查,此后每 5 分钟重复一次,直至胃窦横截面积恢复至基础水平。

结果

非肥胖组{35 [30.0-45.0(20-60)]}和肥胖组{35 [30.0-40.0(25-60)]}儿童的中位(IQR[范围])胃排空时间(分钟)差异无统计学意义(差异中位数 0.0,95%CI-5.0 至 5.0;p=0.563)。两组所有儿童在饮用 3ml/kg 5%葡萄糖清亮液后 60 分钟内,胃窦横截面积和体重校正胃容量均恢复至基础水平。

结论

肥胖和非肥胖儿童的胃排空时间相似,这两组儿童可以在术前 1 小时内给予 3ml/kg 5%葡萄糖清亮液。

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