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小学学龄儿童两种不同奶量的胃排空超声评估。

Ultrasound evaluation of gastric emptying for two different quantities of milk in elementary school-aged children.

作者信息

Liu Xiaofang, Li Xianjun, Liu Guohua, Yan Yuxi, Fang Haotian, Zhang Bin

机构信息

Department of Ultrasound, Children's Hospital Affiliated to Shandong University & Jinan Children's Hospital, Jinan, China.

Pediatric Research Institute, Children's Hospital Affiliated to Shandong University & Jinan Children's Hospital, Jinan, China.

出版信息

Eur J Pediatr. 2025 Jan 30;184(2):163. doi: 10.1007/s00431-025-06001-2.

Abstract

UNLABELLED

Current guidelines recommend 6-h milk fasting in periprocedural settings; however, recent evidence suggests potential overconservativeness and supports more liberal pediatric fasting protocols. This study assessed the gastric emptying of two different milk quantities in elementary school-age children using gastric ultrasonography. This prospective crossover trial involved 30 healthy children who fasted overnight on two separate occasions within one month, consuming either 5 or 10 mL/kg of milk. Gastric ultrasonography assessed the gastric antrum cross-section area in the right lateral decubitus position at intervals until milk emptying. The time for the gastric antrum to return to baseline and the gastric emptying time was recorded. After consuming 5 mL/kg of milk, the time for the gastric antrum to return to baseline varied from 1.5 to 3.5 h (mean: 2.35 ± 0.56 h; median: 2.50 (2.00-2.63) hours). The gastric emptying time ranged from 1.5 to 4.0 h, with the mean and median time of 2.63 ± 0.54 h and 2.50 (2.50-3.00) hours, respectively. With 10 mL/kg of milk, the time for the gastric antrum to return to baseline ranged from 2.0 to 5.0 h, with a mean of 3.35 ± 0.62 h and a median time of 3.50 (3.00-4.00) hours. The gastric emptying time ranged from 2.0 to 5.0 h with a mean and median time of 3.62 ± 0.61 h and 3.50 (3.38-4.00) hours. Subgroup analysis revealed no significant differences between children of different genders or body mass indexes.

CONCLUSION

The gastric return and emptying times are different for both milk quantities, both shorter than the 6-h fasting recommendation, supporting the liberal fasting protocols recommended by the European Society of Anaesthesiology and Intensive Care.

CLINICAL TRIALS REGISTRATION

This trial was registered in the Chinese Clinical Trial Registry (Registration number ChiCTR2300077790) on November 20, 2023.

WHAT IS KNOWN

• The ESAIC guidelines recommend a 4-h fasting period for milk products in periprocedural settings for children.

WHAT IS NEW

• Our research demonstrates that cow's milk is emptied from the stomach within 4 h, supporting the ESAIC recommendations.

摘要

未标注

当前指南建议在围手术期进行6小时禁奶;然而,最近的证据表明这可能过于保守,并支持更宽松的儿科禁食方案。本研究使用胃超声评估了小学年龄段儿童饮用两种不同奶量后的胃排空情况。这项前瞻性交叉试验纳入了30名健康儿童,他们在一个月内分两次进行过夜禁食,分别饮用5或10 mL/kg的牛奶。胃超声在右侧卧位每隔一段时间评估胃窦横截面积,直至牛奶排空。记录胃窦恢复至基线的时间和胃排空时间。饮用5 mL/kg牛奶后,胃窦恢复至基线的时间为1.5至3.5小时(平均:2.35±0.56小时;中位数:2.50(2.00 - 2.63)小时)。胃排空时间为1.5至4.0小时,平均时间和中位数时间分别为2.63±0.54小时和2.50(2.50 - 3.00)小时。饮用10 mL/kg牛奶后,胃窦恢复至基线的时间为2.0至5.0小时,平均为3.35±0.62小时,中位数时间为3.50(3.00 - 4.00)小时。胃排空时间为2.0至5.0小时,平均时间和中位数时间分别为3.62±0.61小时和3.50(3.38 - 4.00)小时。亚组分析显示不同性别或体重指数的儿童之间无显著差异。

结论

两种奶量的胃恢复和排空时间均不同,均短于6小时的禁食建议,支持欧洲麻醉学和重症监护学会推荐的宽松禁食方案。

临床试验注册

本试验于2023年11月20日在中国临床试验注册中心注册(注册号ChiCTR2300077790)。

已知信息

• 欧洲麻醉学和重症监护学会(ESAIC)指南建议儿童在围手术期对奶制品禁食4小时。

新发现

• 我们的研究表明牛奶在4小时内从胃中排空,支持ESAIC的建议。

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