Musculoskeletal Tumor Section, Department of Orthopedic Surgery, Copenhagen University Hospital-Rigshospitalet.
Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital-Bispebjerg; Department of Clinical Medicine, Faculty of Health Science, University of Copenhagen, Denmark.
Acta Orthop. 2023 Mar 6;94:107-114. doi: 10.2340/17453674.2023.10311.
Joint stability after hip replacement (HR) in patients with metastatic bone disease (MBD) is of special importance. Dislocation is the second leading cause of implant revision in HR, while survival after MBD surgery is poor with an expected 1-year survival of around 40%. As few studies have investigated the dislocation risk across different articulation solutions in MBD, we conducted a retrospective study on primary HR for patients with MBD treated in our department.
The primary outcome is the 1-year cumulative incidence of dislocation. We included patients with MBD who received HR at our department in 2003-2019. We excluded patients with partial pelvic reconstruction, total femoral replacement, and revision surgery. We assessed the incidence of dislocation with competing risk analysis with death and implant removal as competing risks.
We included 471 patients. Median follow-up was 6.5 months. The patients received 248 regular total hip arthroplasties (THAs), 117 hemiarthroplasties, 70 constrained liners, and 36 dual mobility liners. Major bone resection (MBR), defined as resection below the lesser trochanter, was performed in 63%. The overall 1-year cumulative incidence of dislocation was 6.2% (95% CI 4.0-8.3). Dislocation stratified by articulating surface was 6.9% (CI 3.7-10) for regular THA, 6.8% (CI 2.3-11) for hemiarthroplasty, 2.9% (CI 0.0-6.8) for constrained liner, and 5.6% (CI 0.0-13) for dual mobility liners. There was no significant difference between patients with and without MBR (p = 0.5).
The 1-year cumulative incidence of dislocation is 6.2% in patients with MBD. Further studies are needed to determine any real benefits of specific articulations on the risk of postoperative dislocation in patients with MBD.
髋关节置换(HR)后关节稳定性对患有转移性骨病(MBD)的患者尤为重要。脱位是 HR 翻修的第二大主要原因,而 MBD 手术后的存活率较低,预计 1 年存活率约为 40%。由于很少有研究调查 MBD 中不同关节解决方案的脱位风险,我们对我院治疗的 MBD 患者进行了一项原发性 HR 的回顾性研究。
主要结果是 1 年累积脱位发生率。我们纳入了 2003 年至 2019 年在我院接受 HR 的 MBD 患者。我们排除了部分骨盆重建、全股骨置换和翻修手术的患者。我们采用竞争风险分析评估脱位发生率,以死亡和假体移除为竞争风险。
我们纳入了 471 例患者。中位随访时间为 6.5 个月。患者接受了 248 例常规全髋关节置换术(THA)、117 例半髋关节置换术、70 例约束衬垫和 36 例双动衬垫。63%的患者行大范围骨切除(MBR),定义为切除小转子以下。总体 1 年累积脱位发生率为 6.2%(95%CI 4.0-8.3)。根据关节面分层,常规 THA 的脱位率为 6.9%(CI 3.7-10),半髋关节置换术为 6.8%(CI 2.3-11),约束衬垫为 2.9%(CI 0.0-6.8),双动衬垫为 5.6%(CI 0.0-13)。有 MBR 和无 MBR 的患者之间差异无统计学意义(p=0.5)。
MBD 患者 1 年累积脱位发生率为 6.2%。需要进一步研究确定特定关节在 MBD 患者术后脱位风险方面的实际获益。