Patel Shrey, Eckembrecher Daphne G, Eckembrecher Francelia J, Hu Jamie K, Gwillim Eran, Nouri Keyvan
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Arch Dermatol Res. 2023 Sep;315(7):2167-2169. doi: 10.1007/s00403-023-02591-9. Epub 2023 Mar 6.
While cardiovascular comorbidities can affect the outcomes of a variety of conditions, to our knowledge, few studies have evaluated their impact on non-melanoma skin cancers (NMSC). We studied the National Inpatient Sample to evaluate the impact of cardiovascular comorbidities on NMSC hospitalizations. Our findings displayed higher cost of care (Beta 5053; SE 1150; P < 0.001), length of stay (Beta 1.8; SE 0.394; P < 0.001), and mortality (aOR 2.51; CI 1.49-4.21; P < 0.001) in patients with NMSC who had an associated cardiovascular comorbidity. Specifically, patients with cerebrovascular disease (aOR 3.52; CI 1.18-10.5; P = 0.024), heart failure (aOR 4.02; CI 2.29-7.05; P < 0.001), complicated hypertension (OR 2.05; CI 1.16-3.61; P = 0.013), and pulmonary circulation disease (aOR 3.33; CI 1.13-9.78; P = 0.029) demonstrated greater odds of mortality.
虽然心血管合并症会影响多种疾病的治疗结果，但据我们所知，很少有研究评估它们对非黑色素瘤皮肤癌（NMSC）的影响。我们研究了全国住院患者样本，以评估心血管合并症对NMSC住院治疗的影响。我们的研究结果显示，患有相关心血管合并症的NMSC患者的护理成本更高（β系数5053；标准误1150；P < 0.001）、住院时间更长（β系数1.8；标准误0.394；P < 0.001）以及死亡率更高（调整后比值比2.51；可信区间1.49 - 4.21；P < 0.001）。具体而言，患有脑血管疾病（调整后比值比3.52；可信区间1.18 - 10.5；P = 0.024）、心力衰竭（调整后比值比4.02；可信区间2.29 - 7.05；P < 0.001）、复杂性高血压（比值比2.05；可信区间1.16 - 3.61；P = 0.013）和肺循环疾病（调整后比值比3.33；可信区间1.13 - 9.78；P = 0.029）的患者死亡几率更高。
