Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Am Surg. 2023 Dec;89(12):5599-5608. doi: 10.1177/00031348231156760. Epub 2023 Mar 6.
Nonoperative management of splenic injuries is recommended. Total splenectomy is the primary operative management, and the current role of splenorrhaphy in splenic salvage is not well delineated.
We reviewed the National Trauma Data Bank (2007-2019) for adult splenic injuries. Operative splenic injury management were compared. We performed bivariate analysis and multivariable logistic regression to estimate the effect of surgical management on mortality.
189,723 patients met the inclusion criteria. Splenic injury management was stable, with 18.2% undergoing a total splenectomy and 1.9% splenorrhaphy. Splenorrhaphy patients had lower crude mortality (2.7% vs 8.3%, < .001) than total splenectomy patients. Failed splenorrhaphy patients had higher crude mortality (10.1% vs 8.3%, P < .001) than patients who underwent initial total splenectomy. Patients who underwent total splenectomy had an adjusted odd of 2.30 (95% CI 1.82-2.92, < .001) for mortality compared to successful splenorrhaphy. Patients who failed splenorrhaphy had an adjusted odd of 2.36 (95% CI 1.19-4.67, < .014) for mortality compared to successful splenorrhaphy.
Adults with splenic injuries requiring operative intervention have twice the odds of mortality when a total splenectomy is performed or when splenorrhaphy fails compared to successful splenorrhaphy.
建议对脾损伤进行非手术治疗。全脾切除术是主要的手术治疗方法,而脾修补术在脾保留中的当前作用尚未明确。
我们回顾了国家创伤数据库(2007-2019 年)中成人脾损伤的资料。比较了手术性脾损伤的处理方法。我们进行了双变量分析和多变量逻辑回归,以估计手术处理对死亡率的影响。
189723 例患者符合纳入标准。脾损伤的处理方法较为稳定,其中 18.2%的患者行全脾切除术,1.9%的患者行脾修补术。脾修补术患者的死亡率明显低于全脾切除术患者(2.7%比 8.3%,<0.001)。脾修补术失败的患者死亡率明显高于初次行全脾切除术的患者(10.1%比 8.3%,P<0.001)。与成功的脾修补术相比,行全脾切除术的患者死亡的调整比值比为 2.30(95%CI 1.82-2.92,<0.001)。脾修补术失败的患者死亡的调整比值比为 2.36(95%CI 1.19-4.67,<0.014)。
与成功的脾修补术相比,需要手术干预的成人脾损伤患者行全脾切除术或脾修补术失败的死亡率增加了两倍。