Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA.
Department of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Plant Cell. 2023 Sep 1;35(9):3173-3186. doi: 10.1093/plcell/koad062.
This review highlights recent literature on biomolecular condensates in plant development and discusses challenges for fully dissecting their functional roles. Plant developmental biology has been inundated with descriptive examples of biomolecular condensate formation, but it is only recently that mechanistic understanding has been forthcoming. Here, we discuss recent examples of potential roles biomolecular condensates play at different stages of the plant life cycle. We group these examples based on putative molecular functions, including sequestering interacting components, enhancing dwell time, and interacting with cytoplasmic biophysical properties in response to environmental change. We explore how these mechanisms could modulate plant development in response to environmental inputs and discuss challenges and opportunities for further research into deciphering molecular mechanisms to better understand the diverse roles that biomolecular condensates exert on life.
这篇综述强调了最近关于植物发育中生物分子凝聚物的文献，并讨论了充分剖析其功能作用的挑战。植物发育生物学中充斥着生物分子凝聚物形成的描述性例子，但直到最近才出现了对其机制的理解。在这里，我们讨论了生物分子凝聚物在植物生命周期不同阶段可能发挥的作用的最新例子。我们根据假定的分子功能将这些例子进行分组，包括隔离相互作用的成分、增加停留时间以及响应环境变化与细胞质生物物理性质相互作用。我们探讨了这些机制如何调节植物发育以响应环境输入，并讨论了进一步研究以更好地理解生物分子凝聚物在生命中发挥的多种作用的分子机制的挑战和机遇。
