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粘连性小肠梗阻手术的经济后果:一项基于人群的研究。

Economic Consequences of Surgery for Adhesive Small Bowel Obstruction: A Population-Based Study.

作者信息

Sakari Thorbjörn, Langenskiöld Sophie, Sköldberg Filip, Karlbom Urban

机构信息

Department of Surgery, Gävle Hospital, Gävle, Sweden.

Department of Surgical Sciences, Uppsala University Hospital, Uppsala, Sweden.

出版信息

Gastroenterol Res Pract. 2023 Feb 25;2023:1844690. doi: 10.1155/2023/1844690. eCollection 2023.

Abstract

BACKGROUND AND AIMS

Most patients develop adhesions after abdominal surgery, some will be hospitalized with small bowel obstruction (SBO), and some also require surgery. The operations and follow-up are expensive, but recent data of costs are scarce. The aim of this study was to describe the direct costs of SBO-surgery and follow-up, in a population-based setting. The association between cost of SBO and peri- and postoperative data was also studied.

METHODS

In a retrospective cohort study, all patients ( = 402) operated for adhesive SBO in Gävleborg and Uppsala counties (2007-2012) were studied. The median follow-up was 8 years. Costs were calculated according to the pricelist of Uppsala University Hospital, Uppsala, Sweden.

RESULTS

Overall total costs were €16.267 million, corresponding to a mean total cost per patient of €40,467 during the studied period. Diffuse adhesions and postoperative complications were associated with increased costs for SBO in a multivariable analysis ( < 0.001). Most costs, about €14 million (85%), arouse in conjunction with the SBO-index surgery period. In-hospital stay was the dominating cost, accounting for 70% of the total costs.

CONCLUSION

Surgery for SBO generates substantial economic burden for healthcare systems. Measures that reduce the incidence of SBO, the frequency of postoperative complication, or the length of stay have the potential to reduce this economic burden. The cost estimates from this study may be valuable for future cost-benefit analyses in intervention studies.

摘要

背景与目的

大多数患者在腹部手术后会形成粘连,部分患者会因小肠梗阻(SBO)住院,还有部分患者需要再次手术。手术及后续治疗费用高昂,但近期关于费用的数据较少。本研究旨在描述基于人群的SBO手术及后续治疗的直接费用。同时也研究了SBO费用与围手术期及术后数据之间的关联。

方法

在一项回顾性队列研究中,对瑞典耶夫勒堡和乌普萨拉郡(2007 - 2012年)因粘连性SBO接受手术的所有患者(n = 402)进行了研究。中位随访时间为8年。费用根据瑞典乌普萨拉大学医院的价格表计算。

结果

总体总费用为1626.7万欧元,相当于研究期间每位患者的平均总费用为40467欧元。在多变量分析中,弥漫性粘连和术后并发症与SBO费用增加相关(P < 0.001)。大部分费用,约1400万欧元(85%),产生于SBO指数手术期间。住院时间是主要费用,占总费用的70%。

结论

SBO手术给医疗系统带来了巨大的经济负担。降低SBO发生率、术后并发症频率或住院时间的措施有可能减轻这种经济负担。本研究的费用估计可能对未来干预研究中的成本效益分析有价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a2b/9985498/e0506dcd34b8/GRP2023-1844690.001.jpg

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