Ivanov Nedyalko N, Garvin Ashley, Mahon Michael J, Stephenson Sean
Department of Dermatology, Beaumont Health Systems, Farmington Hills, MI, USA.
Michigan State University College of Osteopathic Medicine, East Lansing, MI, USA.
Case Rep Dermatol. 2023 Mar 3;15(1):45-50. doi: 10.1159/000529477. eCollection 2023 Jan-Dec.
Eosinophilic fasciitis (EF) is a rare connective tissue disease which closely resembles other scleroderma-like diseases. EF presents with painful swelling and hardening of the distal limbs and is often preceded by a history of strenuous exercise. The marked fascial fibrosis in EF can lead to joint contractures and causes significant morbidity in affected individuals. The authors present a rare case of EF presenting as an ichthyosiform eruption of the bilateral ankles with gradual improvement after the implementation of oral prednisone, hydroxychloroquine, and methotrexate.
嗜酸性筋膜炎（EF）是一种罕见的结缔组织疾病，与其他硬皮病样疾病极为相似。EF表现为远端肢体疼痛性肿胀和硬化，且常伴有剧烈运动史。EF中明显的筋膜纤维化可导致关节挛缩，并给受影响个体带来显著的发病率。作者报告了一例罕见的嗜酸性筋膜炎病例，表现为双侧脚踝鱼鳞病样皮疹，在口服泼尼松、羟氯喹和甲氨蝶呤后逐渐改善。
