Le Alexander, Mathew Anna, Khrais Ayham, Khmelnitsky Irina, Vossough Sima
Internal Medicine, Rutgers University New Jersey Medical School, Newark, USA.
Gastroenterology, Veterans Affairs Medical Center, East Orange, USA.
Cureus. 2023 Feb 2;15(2):e34556. doi: 10.7759/cureus.34556. eCollection 2023 Feb.
Intraductal papillary neoplasm of the bile duct (IPNB) is a rare disease that occurs anywhere along the bile duct. The disease predominantly occurs in Far East Asia and is very rarely diagnosed and documented in western countries. IPNB presents similarly to obstructive biliary pathology; however, patients can be asymptomatic. Surgical resection of IPNB lesions is crucial for patient survival because IPNB is precancerous and can transform into cholangiocarcinoma. Although potentially curative by excision with negative margins, patients who are diagnosed with IPNB need close monitoring for de novo recurrence of IPNB or other pancreatic-biliary neoplasms. In this case, we present an asymptomatic non-Hispanic Caucasian male who was diagnosed with IPNB.
胆管内乳头状肿瘤（IPNB）是一种罕见疾病，可发生于胆管的任何部位。该疾病主要发生在东亚地区，在西方国家很少被诊断和记录。IPNB的表现与梗阻性胆道病变相似；然而，患者可能没有症状。IPNB病变的手术切除对患者生存至关重要，因为IPNB是癌前病变，可转变为胆管癌。尽管通过切缘阴性的切除可能治愈，但被诊断为IPNB的患者需要密切监测IPNB或其他胰胆管肿瘤的新发复发情况。在此病例中，我们介绍了一名无症状的非西班牙裔白人男性，他被诊断为IPNB。
