Department of Pediatrics, Division of Nephrology, Children's Hospital at Montefiore, Albert Einstein College of Medicine, 3326 Bainbridge Avenue, Bronx, NY 10467, USA.
Department of Pediatrics, Division of Nephrology, Children's Hospital at Montefiore, Albert Einstein College of Medicine, 3326 Bainbridge Avenue, Bronx, NY 10467, USA.
Pediatr Clin North Am. 2022 Dec;69(6):1051-1078. doi: 10.1016/j.pcl.2022.08.001. Epub 2022 Oct 29.
Postinfectious glomerulonephritis (PIGN) is a leading cause of acute glomerulonephritis in children. The presentation of PIGN can vary from asymptomatic microscopic hematuria incidentally detected on routine urinalysis to nephritic syndrome and a rapidly progressive glomerulonephritis. Treatment involves supportive care with salt and water restriction, and the use of diuretic and/or antihypertensive medication, depending on the severity of fluid retention and the presence of hypertension. PIGN resolves completely and spontaneously in most children, and the long-term outcomes are typically good with preserved renal function and no recurrence.
感染后肾小球肾炎(PIGN)是儿童急性肾小球肾炎的主要病因。PIGN 的表现形式多种多样,从无症状的镜下血尿(在常规尿检中偶然发现)到肾病综合征和急进性肾小球肾炎。治疗包括支持性治疗,如限制盐和水的摄入,以及根据液体潴留的严重程度和高血压的存在使用利尿剂和/或降压药物。大多数儿童的 PIGN 会完全自发消退,且长期预后通常良好,肾功能保留,无复发。