Reeve T S, Delbridge L, Cohen A, Crummer P
Department of Surgery, University of Sydney at Royal North Shore Hospital, Australia.
Ann Surg. 1987 Dec;206(6):782-6. doi: 10.1097/00000658-198712000-00016.
Total thyroidectomy is an operation that has generally been reserved for the management of differentiated thyroid carcinoma. Over the last decade total thyroidectomy has become used increasingly and is now the preferred option in the authors' unit for the management of multinodular goiter affecting the entire gland. Over the period from 1975 to 1985, 853 thyroidectomies have been performed for multinodular goiter; of these, 115 have been total thyroidectomies. During that time, the incidence of total thyroidectomy for multinodular goiter has increased in percentage terms from 9% in 1975 to 50% in 1985. There have been two cases of permanent hypoparathyroidism and one case of permanent recurrent laryngeal nerve injury, and these occurred in patients who had less than total thyroidectomy. Total thyroidectomy is an appropriate operation for the management of diffuse multinodular goiter where the entire gland is involved because it precludes patients from requiring further surgery for recurrent disease, with its high associated risks. It must be emphasized, however, that protection of the recurrent laryngeal nerve and parathyroid glands must still be paramount in dealing with benign thyroid disease.
全甲状腺切除术通常是用于治疗分化型甲状腺癌的一种手术。在过去十年中,全甲状腺切除术的应用越来越广泛,目前在作者所在科室已成为治疗累及整个腺体的多结节性甲状腺肿的首选术式。在1975年至1985年期间,因多结节性甲状腺肿共施行853例甲状腺切除术,其中115例为全甲状腺切除术。在此期间,多结节性甲状腺肿行全甲状腺切除术的发生率按百分比计算从1975年的9%增至1985年的50%。有2例永久性甲状旁腺功能减退和1例永久性喉返神经损伤,这些均发生在未行全甲状腺切除术的患者中。对于累及整个腺体的弥漫性多结节性甲状腺肿,全甲状腺切除术是一种合适的术式,因为它可避免患者因复发疾病而需再次手术及其高相关风险。然而,必须强调的是,在处理良性甲状腺疾病时,保护喉返神经和甲状旁腺仍然至关重要。