McCready R A, Logan N M, Daugherty M E, Mattingly S S, Crocker C, Hyde G L
University of Kentucky Medical Center, Lexington.
Ann Surg. 1987 Dec;206(6):804-8. doi: 10.1097/00000658-198712000-00020.
With extensive vascular injuries in which a vascular conduit is required, there is controversy as to whether an autogenous or prosthetic graft is preferable. The authors reviewed their experience with 91 extremity arterial injuries in which autogenous tissue was used to repair vascular injuries of the extremities. Twenty-two patients also had concomitant repair of associated venous injuries with autogenous vein grafts. Ten patients required amputations, despite patent grafts in five patients, because of severe muscle necrosis. Two patients had thrombosis of their vein grafts develop in the early postoperative period but did not require amputation. The authors identified only one late vein graft failure in a patient in whom an infected pseudoaneurysm developed. Three patients with extensive soft tissue injuries had infection develop in vein grafts, with subsequent massive bleeding that ultimately required arterial ligation. Among the 22 patients with repair of their venous injuries, occlusion of popliteal vein repairs was documented in two patients and suspected in three others. The remainder of patients had satisfactory results. The excellent results obtained in the vast majority of the authors' patients with extremity vascular injuries reinforces their preference for using autogenous tissue whenever a vascular conduit is required. Exceptions include patients with extensive soft tissue loss precluding adequate graft coverage, the repair of large vessels, and life-threatening emergencies when there is insufficient time to harvest and prepare a vein.
对于需要血管导管的广泛血管损伤,使用自体移植物还是人工血管移植物更好仍存在争议。作者回顾了他们处理91例肢体动脉损伤的经验,这些损伤均采用自体组织修复肢体血管损伤。22例患者还同时采用自体静脉移植物修复相关的静脉损伤。尽管5例患者的移植物通畅,但10例患者因严重肌肉坏死仍需截肢。2例患者术后早期静脉移植物发生血栓形成,但无需截肢。作者仅发现1例晚期静脉移植物失败,该患者发生了感染性假性动脉瘤。3例广泛软组织损伤患者的静脉移植物发生感染,随后出现大量出血,最终需要进行动脉结扎。在22例修复静脉损伤的患者中,有2例记录到腘静脉修复闭塞,另有3例疑似闭塞。其余患者结果满意。作者治疗的绝大多数肢体血管损伤患者获得了良好结果,这强化了他们在需要血管导管时优先使用自体组织的倾向。例外情况包括软组织广泛缺失无法进行充分的移植物覆盖的患者、大血管的修复以及没有足够时间采集和准备静脉的危及生命的紧急情况。