聚四氟乙烯与自体静脉移植物用于污染伤口的血管重建

Polytetrafluoroethylene versus autogenous vein grafts for vascular reconstruction in contaminated wounds.

作者信息

Stone K S, Walshaw R, Sugiyama G T, Dean R E, Dunstan R W

出版信息

Am J Surg. 1984 May;147(5):692-5. doi: 10.1016/0002-9610(84)90144-2.

Abstract

A high incidence of dissolution and disruption of infected autogenous vein grafts has been demonstrated. PTFE, on the other hand, has been shown to maintain its structural integrity in the presence of well-entrenched infection, with a relatively small incidence of anastomotic disruption related to host artery necrosis. In addition, PTFE performed as well as autogenous vein when antibiotics were administered. Therefore, PTFE graft material is advocated for controlled clinical trials in patients with contaminated vascular injuries.

摘要

已证实感染的自体静脉移植物溶解和破坏的发生率很高。另一方面，已表明聚四氟乙烯（PTFE）在存在严重感染的情况下能保持其结构完整性，与宿主动脉坏死相关的吻合口破裂发生率相对较低。此外，在使用抗生素时，PTFE的表现与自体静脉一样好。因此，提倡将PTFE移植材料用于血管损伤受污染患者的对照临床试验。