Department of Oral, Dental and Maxillofacial Surgery, Ataturk University, Erzurum, Turkey.
Department of Oral, Dental and Maxillofacial Surgery, Faculty of Dentistry, Adıyaman University, Adıyaman, Turkey.
BMC Oral Health. 2023 Mar 8;23(1):131. doi: 10.1186/s12903-023-02852-z.
Temporomandibular joint osteoarthritis (TMJ-OA) is a degenerative disease and manifests itself with pain and limitation of movement in the jaws. Arthrocentesis alone or in combination with intraarticular injections is one of the most commonly used treatment methods in these patients. The aim of the study is to examine the effectiveness of arthrocentesis plus tenoxicam injection and to compare it with arthrocentesis alone in patients with TMJ-OA.
Thirty patients with TMJ-OA who were treated randomly with either arthrocentesis plus tenoxicam injection (TX group) or arthrocentesis alone (control group) were examined. Maximum mouth opening (MMO), visual analog scale (VAS) pain values, and joint sounds were the outcome variables, which were evaluated at pre-treatment and at 1, 4, 12, and 24 weeks after treatment. Statistical significance was set at p < 0.05.
The gender distribution and mean age were not significantly different between the two groups. Pain values (p < 0.001), MMO (p < 0.001), and joint sounds (p < 0.001) improved significantly in both groups. However, there was no significant difference between the groups in terms of outcome variables [pain (p = 0.085), MMO (p = 0.174), joint sounds (p = 0.131)].
Arthrocentesis plus tenoxicam injection showed no better outcomes in terms of MMO, pain, and joint sounds compared with arthrocentesis alone in patients with TMJ-OA.
Injection of Tenoxicam Versus Arthrocentesis Alone in the Treatment of Temporomandibular Joint Osteoarthritis, NCT05497570. Registered 11 May 2022. Retrospectively registered, https://register.
gov/prs/app/action/SelectProtocol?sid=S000CD7A&selectaction=Edit&uid=U0006FC4&ts=6&cx=f3anuq.
颞下颌关节骨关节炎（TMJ-OA）是一种退行性疾病，表现为颌骨疼痛和运动受限。关节穿刺术单独或与关节内注射联合使用是这些患者最常用的治疗方法之一。本研究旨在检查关节穿刺术联合替诺昔康注射的疗效，并将其与 TMJ-OA 患者的单纯关节穿刺术进行比较。
将 30 例 TMJ-OA 患者随机分为关节穿刺术联合替诺昔康注射（TX 组）或单纯关节穿刺术（对照组）治疗。最大张口度（MMO）、视觉模拟评分（VAS）疼痛值和关节音为观察指标，分别于治疗前及治疗后 1、4、12 和 24 周进行评估。统计学意义设为 p < 0.05。
两组患者的性别分布和平均年龄无显著差异。两组疼痛值（p < 0.001）、MMO（p < 0.001）和关节音（p < 0.001）均显著改善。然而，两组在观察指标上无显著差异[疼痛（p = 0.085）、MMO（p = 0.174）、关节音（p = 0.131）]。
与单纯关节穿刺术相比，TMJ-OA 患者关节穿刺术联合替诺昔康注射在 MMO、疼痛和关节音方面并未显示出更好的疗效。
替诺昔康注射与单纯关节穿刺术治疗颞下颌关节骨关节炎的比较，NCT05497570。于 2022 年 5 月 11 日注册。回顾性注册，https://register.
gov/prs/app/action/SelectProtocol?sid=S000CD7A&selectaction=Edit&uid=U0006FC4&ts=6&cx=f3anuq。
