Masuda Shinobu, Nakanishi Yoko
Division of Oncologic Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Ohyaguchikami-cho 30-1, Itabashi-ku, Tokyo 173-8610, Japan.
Acta Histochem Cytochem. 2023 Feb 28;56(1):1-8. doi: 10.1267/ahc.22-00050. Epub 2023 Feb 14.
Immunohistochemistry (IHC) has become an indispensable tool in the clinical practices for breast cancer; however, to achieve its standardization, numerous issues need to be overcome. In this review, we describe the development of IHC as an important clinical tool, and the challenges in standardizing IHC results for patients. We also present ideas for resolving the remaining issues and unmet needs, along with future directions.
免疫组织化学(IHC)已成为乳腺癌临床实践中不可或缺的工具;然而,要实现其标准化,还需要克服众多问题。在本综述中,我们描述了免疫组织化学作为一种重要临床工具的发展历程,以及在为患者标准化免疫组织化学结果方面所面临的挑战。我们还提出了解决剩余问题和未满足需求的思路,以及未来的发展方向。