射血分数保留的心力衰竭：简要综述。
Heart Failure with Preserved Ejection Fraction: Concise Review.
机构信息
Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
Department of Cardiology, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
出版信息
S D Med. 2022 Nov;75(11):513-517.
Heart failure with preserved ejection fraction (HFpEF) is a highly prevalent disease, causing a significant burden to the elderly population. Due to the inconsistencies in the standard definition and criteria for diagnosis, HFpEF is often underdiagnosed and left untreated. Although diastolic dysfunction is one of the key driving factors of the disease process, other factors like systolic limitations, endothelial dysfunction, arterial stiffness, and poor ventricular-arterial coupling are also contributing factors. While various treatment modalities have been investigated, the management continues to remain supportive. This review highlights the various American College of Cardiology/American Heart Association and European Society of Cardiology definitions, pathophysiology, and current treatment modalities available for HFpEF.
射血分数保留的心力衰竭（HFpEF）是一种高发疾病，给老年人群带来了巨大负担。由于标准定义和诊断标准不一致，HFpEF 常常被漏诊和未得到治疗。尽管舒张功能障碍是疾病进程的关键驱动因素之一，但其他因素，如收缩功能受限、内皮功能障碍、动脉僵硬和心室-动脉耦联不良，也是致病因素。虽然已经研究了各种治疗方式，但管理仍以支持性治疗为主。这篇综述强调了美国心脏病学会/美国心脏协会和欧洲心脏病学会的各种 HFpEF 定义、病理生理学和现有治疗方式。
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