School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Department of Traditional Chinese Medicine, The First People's Hospital of Yunnan Province; The Affiliated Hospital of Kunming University of Science and Technology, Kunming, China.
BMJ Open. 2023 Mar 9;13(3):e068224. doi: 10.1136/bmjopen-2022-068224.
Breast milk is recognised as the best natural food for neonates, but many women experience postpartum hypogalactia (PH). Randomised trials have found that acupuncture exert therapeutic effect on women with PH. However, systematic reviews on the efficacy and safety of acupuncture are still lacking; therefore, this systematic review aims to evaluate the efficacy and safety of acupuncture for PH.
Six English databases (PubMed, Cochrane Library, EMBASE, EBSCO, Scopus, and Web of Science) and four Chinese databases (China National Knowledge Infrastructure, Wan-Fang, Chinese Biomedical Literature and Chinese Scientific Journal) will be systematically searched from their establishment to 1 September 2022. Randomised controlled trials of the efficacy of acupuncture for PH will be reviewed. The study selection, data extraction and research quality evaluation will be conducted independently by two reviewers. The primary outcome is the change in serum prolactin level from baseline to the end of treatment. Secondary results include milk secretion volume, total effectiveness rate, degree of mammary fullness, rate of exclusive breast feeding, and adverse events. A meta-analysis will be performed using RevMan V.5.4 statistical software. Otherwise, a descriptive analysis will be conducted. The risk of bias will be assessed using the revised Cochrane risk-of-bias tool.
This systematic review protocol does not require ethical approval because it does not include private information/data of the participants. This article will be published in peer-reviewed journals.
CRD42022351849.
母乳被认为是新生儿的最佳天然食物，但许多女性在产后会出现泌乳不足（PH）。随机试验发现，针灸对 PH 女性有治疗作用。然而，目前仍缺乏关于针灸疗效和安全性的系统评价；因此，本系统评价旨在评估针灸治疗 PH 的疗效和安全性。
将从建库起至 2022 年 9 月 1 日，对 6 个英文数据库（PubMed、Cochrane Library、EMBASE、EBSCO、Scopus 和 Web of Science）和 4 个中文数据库（中国知网、万方、中国生物医学文献和中国科技期刊）进行系统检索。将对针灸治疗 PH 疗效的随机对照试验进行综述。研究选择、数据提取和研究质量评价将由两位评审员独立进行。主要结局是从基线到治疗结束时血清催乳素水平的变化。次要结果包括泌乳量、总有效率、乳房充盈程度、纯母乳喂养率和不良事件。使用 RevMan V.5.4 统计软件进行荟萃分析。否则，将进行描述性分析。使用修订后的 Cochrane 偏倚风险工具评估偏倚风险。
本系统评价方案不需要伦理批准，因为它不包括参与者的私人信息/数据。本文将发表在同行评议的期刊上。
PROSPERO 注册号：CRD42022351849。
