Seidemann Lena, Moulla Yusef, Dietrich Arne
Bereich Adipositas-, metabolische und endokrine Chirurgie, Klinik u. Poliklinik für Viszeral‑, Transplantations‑, Thorax- und Gefäßchirurgie, Universitätsklinikum Leipzig, Liebigstr. 20, 04103, Leipzig, Deutschland.
Chirurgie (Heidelb). 2023 Jun;94(6):506-511. doi: 10.1007/s00104-023-01842-9. Epub 2023 Mar 9.
Intestinal bypass procedures are well recognized for their long-term weight reduction and control of metabolic comorbidities. The selection of the length of the small bowel loop has a significant influence on the positive and also negative effects of the chosen procedure but national and international standardization are missing.
The aim of this article is to give an overview of the current evidence on the various intestinal bypass procedures and the influence of the chosen small bowel loop length on the desired and adverse postoperative outcomes. The IFSO 2019 consensus recommendations on the standardization of bariatric surgery and metabolic procedures form the basis of these considerations.
The current literature was searched for comparative studies addressing the question of different small bowel loop lengths in a Roux-en‑Y gastric bypass, one anastomosis gastric bypass, single anastomosis duodenoileal bypass with sleeve gastrectomy and biliopancreatic diversion (with duodenal switch).
Due to the heterogeneity of currently available studies and interindividual differences in total small bowel lengths in humans, it is difficult to give definitive recommendations for the choice of small bowel loop lengths. The longer the biliopancreatic loop (BPL) or the shorter the common channel (CC), the higher is the risk of (severe) malnutrition. To prevent malnutrition, the BPL should not be longer than 200 cm and the CC should have a length of at least 200 cm.
The intestinal bypass procedures recommended in the German S3 guidelines are safe and show good long-term outcomes. As part of the postbariatric follow-up, the nutritional status of patients following an intestinal bypass has to be followed-up on the long term in order to avoid malnutrition preferably prior to a clinical manifestation.
肠道旁路手术因其长期减重及控制代谢合并症而广为人知。小肠袢长度的选择对所选手术的积极和消极影响均有重大影响,但目前缺乏国内和国际标准化。
本文旨在概述目前关于各种肠道旁路手术的证据,以及所选小肠袢长度对术后预期和不良结果的影响。国际肥胖与代谢病外科联盟(IFSO)2019年关于减重手术和代谢手术标准化的共识建议构成了这些考量的基础。
检索当前文献,寻找关于Roux-en-Y胃旁路术、单吻合口胃旁路术、袖状胃切除联合单吻合口十二指肠空肠旁路术以及胆胰分流术(联合十二指肠转位术)中不同小肠袢长度问题的比较研究。
由于现有研究的异质性以及人类小肠总长度的个体差异,很难就小肠袢长度的选择给出明确建议。胆胰袢(BPL)越长或共同通道(CC)越短,(严重)营养不良的风险就越高。为预防营养不良,BPL不应超过200厘米,CC长度应至少为200厘米。
德国S3指南推荐的肠道旁路手术是安全的,且显示出良好的长期效果。作为减重术后随访的一部分,必须长期跟踪接受肠道旁路手术患者的营养状况,以便最好在临床表现出现之前避免营养不良。